Training for brain tumour resection: a realistic model with easy accessibility

Kamp, Marcel A.; Knipps, Johannes; Steiger, Hans‐Jakob; Rapp, Marion; Cornelius, Jan Frédérick; Folke-Sabel, Stefanie; Sabel, Michael

doi:10.1007/s00701-015-2590-6

Cited by 17 publications

(18 citation statements)

References 11 publications

(16 reference statements)

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“…Although it is an in vitro design, it can assist us greatly in our understanding of the preservation of eloquent areas in oncological surgery. The model was assessed by two senior neurosurgeons, five phycians and ten medical students, receiving good and very good overall feedback [16]. A collection of procedures that could prove to be highly useful in the laboratory was also designed by Sabel M. [17].…”

Section: Ovine Modelsmentioning

confidence: 99%

Neurosurgical cadaveric and in vivo large animal training models for cranial and spinal approaches and techniques — a systematic review of the current literature

Morosanu

Nicolae

Moldovan

et al. 2018

Neurol Neurochir Pol.

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Introduction. Due to its high complexity, neurosurgery consists of a demanding learning curve that requires intense training and a deep knowledge of neuroanatomy. Microsurgical skill development can be achieved through various models of simulation, but as human cadaveric models are not always accessible, cadaveric animal models can provide a reliable environment in which to enhance the acquisition of surgical dexterity. The aim of this review was to analyse the current role of animal brains in laboratory training and to assess their correspondence to the procedures performed in humans. Material and methods. A Pubmed literature search was performed to identify all the articles concerning training cranial and spinal techniques on large animal heads. The search terms were 'training model' , and 'neurosurgery' in association with 'animal' , 'sheep' , 'cow' , and 'swine'. The exclusion criteria were articles that were on human brains, experimental fundamental research, or on virtual simulators. Results. The search retrieved 119 articles, of which 25 were relevant to the purpose of this review. Owing to their similar neuroanatomy, bovine, porcine and ovine models prove to be reliable structures in simulating neurosurgical procedures. On bovine skulls, an interhemispheric transcalosal and retrosigmoid approach along with different approaches to the Circle of Willis can be recreated. Ovine model procedures have varied from lumbar discectomies on sheep spines to craniosynostosis surgery, whereas in ex vivo swine models, cadaveric dissections of lateral sulcus, median and posterior fossa have been achieved. Conclusions. Laboratory training models enhance surgical advancements by familiarising trainee surgeons with certain neuroanatomical structures and promoting greater surgical dexterity. The accessibility of animal brains allows trainee surgeons to exercise techniques outside the operating theatre, thus optimising outcomes in human surgical procedures.

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Section: Ovine Modelsmentioning

confidence: 99%

Neurosurgical cadaveric and in vivo large animal training models for cranial and spinal approaches and techniques — a systematic review of the current literature

Morosanu

Nicolae

Moldovan

et al. 2018

Neurol Neurochir Pol.

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“…Considering these characteristics, cadaveric sheep brains have been used as teaching material for mammalian cerebral anatomy (16) and several neurosurgical techniques have been developed and tested through this neurosurgical animal model (17).…”

Section: Discussionmentioning

confidence: 99%

Morphometric Study of The Ventricular Indexes in Healthy Ovine Brain Using MRI

Trovatelli¹,

Spediacci²,

Castellano³

et al. 2020

Preprint

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BackgroundSheep (Ovis aries) have been largely used as animal models in a multitude of specialties in biomedical research. The similarity to human brain anatomy in terms of brain size, skull features, and gyrification index, gives to ovine as a large animal model a better translational value than small animal models in neuroscience. Despite this evidence and the availability of advanced imaging techniques, morphometric brain studies are lacking. We herein present the morphometric ovine brain indexes and anatomical measures developed by two observers in a double-blinded study and validated via an intra- and inter-observer analysis. ResultsFor this retrospective study, T1-weighted Magnetic Resonance Imaging (MRI) scans were performed at 1.5T on 15 sheep, under general anaesthesia. The animals were female Ovis aries, in the age of 18-24 months. Two observers assessed the scans, twice time each. The statistical analysis of intra-observer and inter-observer agreement was obtained via the Bland-Altman plot and Spearman rank correlation test.The results are as follows (mean±Standard deviation): Indexes: Bifrontal 0,338 ± 0,032 cm; Bicaudate 0,080 ± 0,012 cm; Evans’ 0,218 ± 0,035 cm; Ventricular 0,241 ± 0,039 cm; Huckman 1,693 ± 0,174 cm; Cella Media 0,096 ± 0,037 cm; Third ventricle ratio 0,040 ± 0,007 cm. Anatomical measures: Fourth ventricle length 0,295 ± 0,073 cm; Fourth ventricle width 0,344 ± 0,074 cm; Left lateral ventricle 4,175 ± 0,275 cm; Right lateral ventricle 4,182 ± 0,269 cm; Frontal horn length 1,795 ± 0,303 cm; Interventricular foramen left 1,794 ± 0,301cm; Interventricular foramen right 1,78 ± 0,317 cm.ConclusionsThe present study provides baseline values of linear indexes of the ventricles in the ovine models. The acquisition of these data contributes to filling the knowledge void on important anatomical and morphological features of the sheep brain.

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“…Such agents may be localized to form sharply delimited masses that mimic cerebral metastases or be diffuse to migrate to the surrounding brain tissue and resemble glioma. These artificial lesions can then be excised using the standard brain tumor microsurgical steps [16,27,30].…”

Section: Task-oriented Simulation Trainingmentioning

confidence: 99%

The use of non-living animals as simulation models for cranial neurosurgical procedures: a literature review

et al. 2020

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Simulation plays a pivotal role in neurosurgical training by allowing trainees to develop the requisite expertise to enhance patient safety. Several models have been used for simulation purposes. Non-living animal models offer a range of benefits, including affordability, availability, biological texture, and a comparable similarity to human anatomy. In this paper, we review the available literature on the use of non-living animals in neurosurgical simulation training. We aim to answer the following questions: (1) what animals have been used so far, (2) what neurosurgical approaches have been simulated, (3) what were the trainee tasks, and (4) what was the experience of the authors with these models. A search of the PubMed Medline database was performed to identify studies that examined the use of non-living animals in cranial neurosurgical simulation between 1990 and 2020. Our initial search yielded a total of 70 results. After careful screening, we included 22 articles for qualitative analysis. We compared the reports in terms of the (1) animal used, (2) type of surgery, and (3) trainee tasks. All articles were published between 2003 and 2019. These simulations were performed on three types of animals, namely sheep, cow, and swine. All authors designed specific, task-oriented approaches and concluded that the models used were adequate for replicating the surgical approaches. Simulation on non-living animal heads has recently gained popularity in the field of neurosurgical training. Non-living animal models are an increasingly attractive option for cranial neurosurgical simulation training. These models enable the acquisition and refinement of surgical skills, with the added benefits of accessibility and cost-effectiveness. To date, 16 different microneurosurgical cranial approaches have been replicated on three non-living animal models, including sheep, cows, and swine. This review summarizes the experience reported with the use of non-living animal models as alternative laboratory tools for cranial neurosurgical training, with particular attention to the set of tasks that could be performed on them.

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Training for brain tumour resection: a realistic model with easy accessibility

Cited by 17 publications

References 11 publications

Neurosurgical cadaveric and in vivo large animal training models for cranial and spinal approaches and techniques — a systematic review of the current literature

Neurosurgical cadaveric and in vivo large animal training models for cranial and spinal approaches and techniques — a systematic review of the current literature

Morphometric Study of The Ventricular Indexes in Healthy Ovine Brain Using MRI

The use of non-living animals as simulation models for cranial neurosurgical procedures: a literature review

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