Traditional Tibetan medicine to fight against COVID-19: Basic theory and therapeutic drugs

Zhang, Kun; Wang, Lijie; Peng, Jiayan; Sangji, Kangzhuo; Luo, Yuting; Zeng, Yujiao; Zeweng, Yong-Zhong; Fan, Gang

doi:10.3389/fphar.2023.1098253

Cited by 6 publications

(5 citation statements)

References 66 publications

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“…According to the chemical structure, the alkaloids are divided into three subgroups: 7,8secoberbines-tricyclic (39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49) and tetracyclic (50-58); 7,8-14,7-bissecoberbine-peshawarine (59) and 6,7-secoberbines (60-66) [53]. All tricyclic 7,8-secoberbines in the Hypecoum species have substitutions at C-8 with -CH 2 OH or -COOH groups.…”

Section: Secoberbine Alkaloidsmentioning

confidence: 99%

Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Kostova,

Doncheva

2023

Diversity

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Genus Hypecoum Tourn. ex L. belongs to the poppy family Papaveraceae and comprises about 19 species occurring in Europe, Northern Africa and Asia. Hypecoum species have been widely used in traditional medicine as antipyretic, analgesic and anti-inflammatory remedies. Their effects are associated with the biologically and pharmacologically active isoquinoline alkaloids in them, such as protopines, protoberberines, benzophenanthridines, aporphines, simple isoquinolines, secoberbines, spirobenzylisoquinolines and others. In this study, we aimed to review and organize information on ethnomedicinal, phytochemical, chemotaxonomical and pharmacological studies of alkaloids and extracts obtained from Hypecoum plants, and to suggest opportunities for further research.

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Section: Secoberbine Alkaloidsmentioning

confidence: 99%

Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Kostova,

Doncheva

2023

Diversity

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“…The ten narrative reviews 10,[12][13][14]16,19,20,25,32,33 that examined herbs used in traditional Chinese, 10,12,13,14,16,19,32 Tibetan, 33 and Thai 10 medicine, and Ayurveda 12,20,25 highlighted the antiviral, 10,13,14,16,20,25,32,33 antiinflammatory, 10,13,32,33 immunomodulatory, 12,13,14,16,20,33 and hepa topro tective 16 properties of a broad variety of herbs and formulations.…”

Section: Plants Used In Traditional Systems Of Medicine (Chinese Tibe...mentioning

confidence: 99%

Herbal Medicine and COVID-19: An Umbrella Review

Oakes,

Saunders,

Lloyd

et al. 2023

CANDJ

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Background: Most systems of traditional medicine have been using herbal medicines to prevent and treat acute respiratory conditions and various other conditions for centuries. The aim of this project is to identify and examine the systematic and narrative reviews reporting on the therapeutic use of herbal medicines as it relates to the prevention and treatment of COVID-19 and long COVID. Methods: This paper is part of an umbrella review of studies related to natural health products and natural therapies for the prevention or treatment of COVID-19. It is a follow-up to a live review that was conducted by the World Naturopathic Federation between May 2022 and May 2023. PubMed and Google Scholar were searched for systematic and narrative reviews that met defined quality criteria. Results: Over half of the initial systematic reviews were excluded as they did not meet the inclusion and AMSTAR criteria. The final paper included 25 narrative reviews and 41 systematic reviews (SR), with half of the SRs reporting on the safety of herbal interventions. Various therapeutic properties of over 60 herbal medicines were outlined, some individually and most of them as part of herbal formula (combinations). Conclusion/Summary: Herbal interventions demonstrated statistically significant improved recovery in patients with COVID-19. The most common therapeutic properties identified were immunological properties, anti-inflammatory, anti- microbial, and antioxidant while the most frequently investigated herbs were Glycyrrhiza glabra/uralensis, Tinospora cordifolia, and Curcuma longa. More attention is needed on the regulation of herbal medicines, the quality of research, and the safety of herbal medicines.

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“…At present, there are scholars have sorted out Tibetan medicine prescriptions for COVID-19, providing important information for the basic research, clinical application, and drug development of traditional medicines for the treatment of COVID-19 or other infectious diseases ( Zhang et al, 2023 ). Biological activities of Gentianeae in Tibetan Medicine ( Chi et al, 2021 ) and Tibetan medicine Bang Jiang ( Li et al, 2023 ) have been compiled.…”

Section: Introductionmentioning

confidence: 99%

Traditional Tibetan medicine: therapeutic potential in lung diseases

Li,

Huang

et al. 2024

Front. Pharmacol.

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Lung diseases have become a major threat to human health worldwide. Despite advances in treatment and intervention in recent years, effective drugs are still lacking for many lung diseases. As a traditional natural medicine, Tibetan medicine has had a long history of medicinal use in ethnic minority areas, and from ancient times to the present, it has a good effect on the treatment of lung diseases and has attracted more and more attention. In this review, a total of 586 Tibetan medicines were compiled through literature research of 25 classical works on Tibetan medicine, drug standards, and some Chinese and English databases. Among them, 33 Tibetan medicines have been studied to show their effectiveness in treating lung diseases. To investigate the uses of these Tibetan medicines in greater depth, we have reviewed the ethnomedicinal, phytochemical and pharmacological properties of the four commonly used Tibetan medicines for lung diseases (rhodiola, gentian, sea buckthorn, liexiang dujuan) and the five most frequently used Tibetan medicines (safflower, licorice, sandalwood, costus, myrobalan). It is expected to provide some reference for the development of new drugs of lung diseases in the future.

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Traditional Tibetan medicine to fight against COVID-19: Basic theory and therapeutic drugs

Cited by 6 publications

References 66 publications

Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Herbal Medicine and COVID-19: An Umbrella Review

Traditional Tibetan medicine: therapeutic potential in lung diseases

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