BackgroundA novel coronavirus (2019-nCoV) has raised world concern since it emerged in Wuhan Hubei China in December, 2019. The infection may result into severe pneumonia with clusters illness onsets. Its impacts on public health make it paramount to clarify the clinical features with other pneumonias.

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urgently demanded. Lithium ion batteries (LIBs) have been widely utilized in portable electronic devices due to their large energy densities, high efficiency, and light weight; [1] however, uneven distribution and insufficient lithium resource on earth make LIBs not sufficiently affordable in future energy storage systems, especially in the large-scale energy storage scenarios. As a promising alternative, sodium ion batteries (SIBs) have recently gained considerable interests owing to the abundant sodium resource and the similar rockingchair electrochemistry mechanism to LIBs. [2] However, the differences in size and ionization environment between the Na and lithium atoms have brought major challenges in the development of SIBs, among which the failure of commercial graphite anode to insert Na + is the most critical one due to the larger ionic radius of Na atom. [3] To this end, extensive explorations have been carried out to screen promising anode candidates for SIBs which include titanium-based oxides, [4,5] transition metal borates, [6] metal sulfides, [7,8] carbon materials [9][10][11] as well as their composite structures. [12,13] Among these, carbonaceous materials have attracted most attentions because of their cost-effective preparations, highly tunable physicochemical structures, and negligible environmental harms. [14] To reveal the structure-performance relationships, various Na + storage mechanisms in carbonaceous anodes have been proposed, which can be summarized as the individual or synergetic improvements on multiple sodiation processes including insertion, adsorption, and ultramicropore filling. [15][16][17][18] Correspondingly, engineering the multiscale nanostructures in carbon materials has been the research focus which can be refined as follows: i) expanding interlayer spacing between graphene layers to allow for large-radius Na + insertion (for instance, hard carbon, [19] and expanded graphite [20] ); ii) optimizing pore network to facilitate Na + transportation or storage (for example, hard carbon with closed pore [21,22] and ultramicroporous carbon [9,23] ); iii) introducing heteroatoms (e.g., S, P, B, N, F-doped [11,[24][25][26][27] or codoped carbons [28][29][30] ) or defects (e.g., defect-rich soft carbon [31] ) into carbon lattice to induce capacitive adsorption or reactions; iv) constructing favorable 3DOxygen-containing groups in carbon materials have been shown to affect the carbon anode performance of sodium ion batteries; however, precise identification of the correlation between specific oxygen specie and Na + storage behavior still remains challenging as various oxygen groups coexist in the carbon framework. Herein, a postengineering method via a mechanochemistry process is developed to achieve accurate doping of (20.12 at%) carboxyl groups in a carbon framework. The constructed carbon anode delivers all-round improvements in Na + storage properties in terms of a large reversible capacity (382 mAg −1 at 30 mA g −1 ), an excellent rate capability (153 mAg −1 at 2 A g −1 ) as well ...

BackgroundTo explore the relationship between enteroviruses and hospitalized children with hand, foot and mouth disease (HFMD) complicated with nervous system disease. 234 hospitalized HFMD patients treated in Shengjing Hospital, Liaoning Province were analyzed retrospectively. Based on the presence and severity of nervous system disease, the patients were grouped as follows: general patients, severely ill patients, critically ill patients and fatal patients. Based on the detected pathogen, the patients were grouped as follows: Enterovirus 71 (EV71) infection, coxsackie A16 (CA16) infection and other enterovirus (OE) infection.ResultsOf the 423 hospitalized patients, most were admitted in July 2010(129/423, 30.5%). Enteroviruses were detected in 177(41.8%). 272/423 patients were male (64.3%), and fatal patients had the greatest proportion of male patients (p < 0.05). EV71 infection was found in 89/423 patients (21%). CA16 infection was detected in 8/423 patients (16.1%). Compared to group CA16, patients in group EV71 were hospitalized earlier, and the duration of hospitalization was longer (p < 0.05). Of the 92 patients with nervous system damage, 65 were infected with EV71 and 19 were infected with CA16. Among these CA16 infected patients, 2 had brainstem encephalitis and 1 had AFP. There were more patients with nervous system dysfunction in group EV71 than in groups CA16 or OE (p < 0.05). The 5 fatalities all occurred in group EV71 patients (p < 0.05). Infection with EV71 was most likely to cause neurogenic pulmonary edema (p < 0.05). Patients in group EV71 had a higher rate of suffering from coma and limb movement disorder than patients in groups CA16 or OE (p < 0.05).ConclusionThe disease progresses faster in EV71-infected HFMD patients. These patients are more likely to suffer nervous system damage, neurogenic pulmonary edema, severe sequelae or death. CA16 and other enteroviruses can also cause HFMD with severe nervous system complications.

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To circumvent the imbalances of electrochemical kinetics and capacity between Li storage anodes and capacitive cathodes for lithium-ion capacitors (LICs), we herein demonstrate an efficient solution by boosting the capacitive charge-storage contributions of carbon electrodes to construct a high-performance LIC. Such a strategy is achieved by the in situ and high-level doping of nitrogen atoms into carbon nanospheres (ANCS), which increases the carbon defects and active sites, inducing more rapidly capacitive charge-storage contributions for both Li storage anodes and PF storage cathodes. High-level nitrogen-doping-induced capacitive enhancement is successfully evidenced by the construction of a symmetric supercapacitor using commercial organic electrolytes. Coupling a pre-lithiated ANCS anode with a fresh ANCS cathode enables a full-carbon LIC with a high operating voltage of 4.5 V and high energy and power densities thereof. The assembled LIC device delivers high energy densities of 206.7 and 115.4 Wh kg at power densities of 0.225 and 22.5 kW kg, respectively, as well as an unprecedented high-power cycling stability with only 0.0013% capacitance decay per cycle within 10 000 cycles at a high power output of 9 kW kg.