Trace Elements in Living Systems: From Beneficial to Toxic Effects

Mikulewicz, Marcin; Chojnacka, Katarzyna; Kawala, Beata; Gredes, Tomasz

doi:10.1155/2017/8297814

Cited by 17 publications

(11 citation statements)

References 12 publications

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“…Most of these trace elements are the functional part of enzymes. Yet, intakes of a large amount of trace elements are noxious to both human and animals (Mikulewicz et al, 2017 ). For instance, trivalent chromium is responsible for glucose metabolism by acting as a cofactor for insulin action.…”

Section: Role Of Antioxidants In the Prevention Of Age-related Diseasmentioning

confidence: 99%

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

et al. 2018

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Aging is the progressive loss of organ and tissue function over time. Growing older is positively linked to cognitive and biological degeneration such as physical frailty, psychological impairment, and cognitive decline. Oxidative stress is considered as an imbalance between pro- and antioxidant species, which results in molecular and cellular damage. Oxidative stress plays a crucial role in the development of age-related diseases. Emerging research evidence has suggested that antioxidant can control the autoxidation by interrupting the propagation of free radicals or by inhibiting the formation of free radicals and subsequently reduce oxidative stress, improve immune function, and increase healthy longevity. Indeed, oxidation damage is highly dependent on the inherited or acquired defects in enzymes involved in the redox-mediated signaling pathways. Therefore, the role of molecules with antioxidant activity that promote healthy aging and counteract oxidative stress is worth to discuss further. Of particular interest in this article, we highlighted the molecular mechanisms of antioxidants involved in the prevention of age-related diseases. Taken together, a better understanding of the role of antioxidants involved in redox modulation of inflammation would provide a useful approach for potential interventions, and subsequently promoting healthy longevity.

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Section: Role Of Antioxidants In the Prevention Of Age-related Diseasmentioning

confidence: 99%

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

et al. 2018

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“…Calcium silicate-based sealers, including more reactive calcium-silicate-based bioactive glass, known as bioactive root canal sealers, have been recently introduced [ 30 , 31 , 32 ]. Bioactive glass has been mainly used for dental hard tissue regeneration; however, it has also recently shown promise for the repair of several complex tissues [ 33 ].…”

Section: Introductionmentioning

confidence: 99%

Physical Properties and Biofunctionalities of Bioactive Root Canal Sealers In Vitro

Kim

Lee

et al. 2020

Nanomaterials

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Calcium silicate-based bioactive glass has received significant attention for use in various biomedical applications due to its excellent bioactivity and biocompatibility. However, the bioactivity of calcium silicate nanoparticle-incorporated bioactive dental sealer is not much explored. Herein, three commercially available bioactive root canal sealers (Endoseal MTA (EDS), Well-Root ST (WST), and Nishika Canal Sealer BG (NBG)) were compared with a resin-based control sealer (AH Plus (AHP)) in terms of physical, chemical, and biological properties. EDS and NBG showed 200 to 400 nm and 100 to 200 nm nanoparticle incorporation in the SEM image, respectively, and WST and NBG showed mineral deposition in Hank’s balanced salt solution after 28 days. The flowability and film thickness of all products met the ISO 3107 standard. Water contact angle, linear dimensional changes, and calcium and silicate ion release were significantly different among groups. All bioactive root canal sealers released calcium ions, while NBG released ~10 times more silicon ions than the other bioactive root canal sealers. Under the cytocompatible extraction range, NBG showed prominent cytocompatibility, osteogenecity, and angiogenecity compared to other sealers in vitro. These results indicate that calcium silicate nanoparticle incorporation in dental sealers could be a potential strategy for dental periapical tissue regeneration.

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“…It showed that the growth and ecological environment of the medicinal materials were good and no pollution. e contents of elements have the great significance within the aspects of the plant physiology, the structure and efficacy of medicinal materials, and the ecological environment [20]. is research can provide a determination basis of trace elements in Corydalis conspersa and Corydalis linarioides so as to reveal the relationship between the functions of trace elements and plant growth through the further researches.…”

Section: Discussionmentioning

confidence: 99%

Determination of Trace Elements in Corydalis conspersa and Corydalis linarioides by ICP-AES

Cai²,

Chen

et al. 2020

Journal of Chemistry

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In order to establish a method for the simultaneous determination of trace elements Al, As, B, Ca, Cr, Cu, Fe, K, Li, Mg, Mn, Na, Ni, P, Si, Ti, and Zn in Corydalis conspersa and Corydalis linarioides, we collected the samples from different areas and treated with acid hydrolysis into tissues to be detected by the way of inductively coupled plasma-atomic emission spectrometry compared with the standard element control method. We can know that the contents of Al, Ca, Fe, K, Mg, Na, and P in roots, stems, leaves, and flowers were higher. The contents of elements in different tissues and areas were as follows: flower > leaf > stem > root, Zeku County > Guide County > Nangqian County > Henan County. Among them, the contents of each element in the flowers of Maixiu Forest Farm were higher, while the contents of B, Cr, Cu, Li, Mn, Ni, Si, Ti, and Zn in roots, stems, and leaves of other areas were lower. The contents of heavy metal elements complied with the limit degree. A 3-factor model was obtained by principal component analysis which could clarify 82.46% of the total experimental data; the factors of Al, Fe, Mg, Na, P, Ca, Cu, Si, and Zn had great influence on the efficacy of 21 kinds of medicinal materials. Cluster analysis classified the samples into three categories; the flowers of Corydalis conspersa and stems of Corydalis linarioides from different collection areas are clustered containing high contents of type 1 and 3 characteristic components; the roots, stems, and leaves from other collection areas are clustered with low contents of 1 and 2 characteristic components. It can be used for the determination of trace elements in Corydalis conspersa and Corydalis linarioides to provide effective basis for revealing the function of trace elements with plant growth.

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Trace Elements in Living Systems: From Beneficial to Toxic Effects

Cited by 17 publications

References 12 publications

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

Physical Properties and Biofunctionalities of Bioactive Root Canal Sealers In Vitro

Determination of Trace Elements in Corydalis conspersa and Corydalis linarioides by ICP-AES

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