Trace element levels in blood and associated factors in adults living in the metropolitan area of São Paulo, Brazil

Takeda, Simone Harue Kimura; Kuno, Rúbia; Barbosa, Fernando

doi:10.1016/j.jtemb.2017.09.005

Cited by 24 publications

(14 citation statements)

References 52 publications

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“…A sample of 18-74 year-old participants (n=240) from Maringa demonstrated no significant difference in serum As between males (GM = 1.15 μg/L) and females (GM = 1.19 μg/L) although serum As was negatively correlated with age in both males (r= −0.22) and females (r = −0.30) (Rocha et al, 2016). In another study of 374 adults (18-65 years) conducted in Sao Paulo area, slightly higher exposure was reported even though the difference between BAs in males (GM= 3.5 μg/L) and females (GM= 3.7 μg/L) was non-significant (Takeda et al, 2017). BAs was also used to determine reference values and relationship with sociodemographic characteristics in another urban study in Brazil.…”

Section: Introductionmentioning

confidence: 92%

Health effects of arsenic exposure in Latin America: An overview of the past eight years of research

Khan

Chakraborty

Bundschuh

et al. 2020

Science of The Total Environment

101

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Studies conducted over the past eight years in Latin America (LA) have continued to produce new knowledge regarding health impacts of arsenic (As) in drinking water. We conducted a systematic review of 92 peer-reviewed English articles published between 2011 and 2018 to expand our understanding on these health effects. Majority of the LA studies on As have been conducted in Chile and Mexico. Additional data have emerged from As-exposed populations in Argentina,

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Section: Introductionmentioning

confidence: 92%

Health effects of arsenic exposure in Latin America: An overview of the past eight years of research

Khan

Chakraborty

Bundschuh

et al. 2020

Science of The Total Environment

101

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“…Due to the influences of different regions, environments, and lifestyles [ 7 ], the lack of a reliable reference for general population has still remained tangible. Different countries across the world have set their own references for specific populations, including Canada [ 8 ], Czech Republic [ 9 , 10 ], Brazil [ 11 ], Germany [ 12 ], Italy [ 13 , 14 ], etc. studies pointed out that differences in reference values are caused by overall differences in individuals’ age, sex, country of origin, food and drinking habits, smoking history, medication, etc.…”

Section: Introductionmentioning

confidence: 99%

Determination of 11 minerals in children using inductively coupled plasma mass spectrometry

Wang

et al. 2021

BMC Pediatr

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Background Minerals play an important role in children’s growth and cognition. In this study, our aim was to establish reference intervals of mineral level in Children of Liaoning province (China) and provide a reliable basis for future preventive healthcare guidelines. Methods Random samples of 2217 healthy children aged 0–15 years who were referred for routine hospital laboratory examinations in the cities of Shenyang, Fushun, Fuxin, Benxi, Chaoyang and Lingyuan were invited to participate in the study. Serum levels of Calcium (Ca), Iron (Fe), Zinc (Zn), Magnesium (Mg), Copper (Cu), Manganese (Mn), Selenium (Se), Mercury (Hg), Nickel (Ni), Cobalt (Co), and Lithium (Li) were determined by inductively coupled plasma mass spectrometer(ICP-MS). Results Sex-related significant differences in the serum concentrations of the Mg and Cu (P < 0.05). Age-related significant differences were found in serum levels of Ca, Fe, Zn, Mg, Cu and Mn (P < 0.05) and the concentrations of 9 minerals (Ca, Mg, Cu, Mn,Se,Hg,Ni,Co and Li in serum varied from season to season (P < 0.05). The Spearman correlation matrix of 11 minerals was shown as a heat map, the correlations between Ca-Zn, Ca-Mg, Fe-Zn, Fe-Se, Mn-Ni, Se-Hg, Se-Ni, Hg-Ni, and Ni-Co, Ni-Li were the strongest compared with others. Conclusions The reference intervals of serum 11 minerals for children should considering the sex, age and season, which may be useful for decisive diagnoses of abnormality of the 11minerals and the related diseases.

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“…Nevertheless, the preferred approach for trace elements’ assessment is by non- or less-invasive techniques where sample collection is concerned. As such, testing for circulating levels of trace elements in the blood has been commonly opted in most studies [[22], [23], [24], [25]].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous analysis of 25 trace elements in micro volume of human serum by inductively coupled plasma mass spectrometry (ICP-MS)

Nawi

Chin

Jamal

2020

Practical Laboratory Medicine

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IntroductionIn recent years, trace elements have gained importance as biomarkers in many chronic diseases. Unfortunately, the requirement for sample volume increases with the extent of investigation either for diagnosis or elucidating the mechanism of the disease. Here, we describe the method development and validation for simultaneous determination of 25 trace elements (lithium [Li], beryllium [Be], magnesium [Mg], aluminium [Al], vanadium [V], chromium [Cr], manganese [Mn], iron [Fe], cobalt [Co], nickel [Ni], copper [Cu], zinc [Zn], gallium [Ga], arsenic [As], selenium [Se], rubidium [Rb], strontium [Sr], silver [Ag], cadmium [Cd], caesium [Cs], barium [Ba], mercury [Hg], thallium [Tl], lead [Pb], uranium [U]) using only 20 μL of human serum.MethodsSerum samples were digested with nitric acid and hydrochloric acid (ratio 1:1, v/v) and analysed by inductively coupled plasma–mass spectrometry (ICP-MS). Seronorm®, a human-derived serum control material was used as quality control samples.ResultsThe coefficient of variations for both intra- and inter-day precisions were consistently <15% for all elements. The validated method was later tested on 30 human serum samples to evaluate its applicability.ConclusionWe have successfully developed and validated a precise and accurate analytical method for determining 25 trace elements requiring very low volume of human serum.

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Trace element levels in blood and associated factors in adults living in the metropolitan area of São Paulo, Brazil

Cited by 24 publications

References 52 publications

Health effects of arsenic exposure in Latin America: An overview of the past eight years of research

Health effects of arsenic exposure in Latin America: An overview of the past eight years of research

Determination of 11 minerals in children using inductively coupled plasma mass spectrometry

Simultaneous analysis of 25 trace elements in micro volume of human serum by inductively coupled plasma mass spectrometry (ICP-MS)

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