“…Histological endpoints associated with bone modeling and remodeling 1 vary among and within bones (Amling et al, 1996;Amprino and Marotti, 1964;Harris et al, 1968;Lee et al, 1965;Marotti, 1976;Martin et al, 1980;Soni, 1968;Wronski et al, 1981). For single bones, the range of inter-and intra-individual variation is most extensively documented for specific ribs (Frost, 1969;Tommerup et al, 1991) and the ilium (de Vernejoul et al, 1981;Ellis and Peart, 1972;Hardt and Jee, 1982;Malluche et al, 1982;Melson et al, 1978;Savage et al, 1991;Whitehouse, 1977) due to past (ribs) or current (ilium) application in diagnostic clinical evaluation (Bordier and Tun Chot, 1972;Melson and Mosekilde, 1981;Recker, 1994;Santoro and Frost, 1967). Quantitative documentation of normal histological variation in long bone transverse sections is rather limited (Martin et al, 1980;Raab et al, 1991), even though long bones are used commonly in assessments of bone response to mechanical loading (Hert et al, 1972;O'Connor et al, 1982;Raab et al, 1991).…”