Toxoplasma gondii, HCV, and HBV seroprevalence and co‐infection among HIV‐positive and ‐negative pregnant women in Burkina Faso

Simporé, Jacques; Savadogo, Aly; Ilboudo, D.; Nadambega, Marie Christelle; Esposito, Maria; Yara, Justine; Pignatelli, Salvatore; Pietra, Virginio; Musumeci, Salvatore

doi:10.1002/jmv.20615

Cited by 92 publications

(81 citation statements)

References 13 publications

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“…The T. gondii seroprevalence estimated for human population varies greatly among different countries, among different geographical areas within the same country, and among different ethnic groups living in the same area (5). In this study the prevalence of Toxoplasma gondii antibodies in an HIV-positive population at the UTHC Yaoundé was found to be 69.9%.…”

Section: Discussionmentioning

confidence: 56%

Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

Assob¹,

Njunda²,

Nsagha³

et al. 2011

Af J Clin Exp Micro

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Toxoplasmosis is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. This work was carried out to determine the seroprevalence of toxoplasma antibodies (IgM and IgG) in HIV/AIDS patients attending the Yaoundé University Teaching Hospital (UTH) in Cameroon. Sera were collected from 133 HIV/AIDS patients at the out-patient department and the ELISA technique was employed serologically to determine toxoplasma antibodies. Of the 133 patients 83 (62.4%) were females and 59 (37.6%) were males; ninety three (69.9%) were positive for toxoplasma antibodies. Fourteen (10.8%) of the 93 of seropositive patients presented with both IgG and IgM-antibodies in their sera while fifty six (42.1%) and 8 (6.0%) were only sero-positive for toxoplasma IgG or IgM-antibody respectively This rate of infection was not dependent on the patient's sex or age (X 2 =11.49, P>0.05). The data provides enough evidence to conclude that 64.7% of the positive cases were due to reactivated infection.

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Section: Discussionmentioning

confidence: 56%

Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

Assob¹,

Njunda²,

Nsagha³

et al. 2011

Af J Clin Exp Micro

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show abstract

“…However, other studies have reported prevalence rates of 4.0% and 6.3% in Koudougou blood donors and regional blood transfusion centers of Burkina Faso, respectively (7,26). The prevalence rates ranging between 2.0% and 5.4% have been also reported among pregnant women in Ouagadougou (6,11,27,28).…”

Section: Discussionmentioning

confidence: 96%

“…Burkina Faso is a country with high HBV endemicity (prevalence > 8%) (6). In previous research, the prevalence of HBV infection was 14.5% in the general population and varied between 13% and 19% among blood donors (7,8).…”

Section: Introductionmentioning

confidence: 95%

World Hepatitis Day in Burkina Faso, 2016: Awareness, Screening, Identification of HBV Markers, HBV/HCV Coinfection, and Vaccination

et al. 2017

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Background: Hepatitis B virus (HBV) can cause chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Coinfection with hepatitis C virus (HCV)/HBV leads to a higher risk of liver damage. Development of HBV awareness campaigns could reduce the prevalence of this disease and limit the consequences. Objectives: The aim of this study was to sensitize, detect, and identify HBV markers and propose vaccination for people not infected with HBV. Methods: With the support of "SOS Hepatitis Burkina" association, an HBV screening program, available for all volunteers, was implemented in several localities of Ouagadougou and the surroundings. A rapid HBsAg detection test was performed on 2207 subjects, who voluntarily answered a series of questions. A rapid detection test of HCV antibodies was performed in HBsAg-positive cases. HBV markers were also determined in HBsAg-positive cases.Results: In a sample of 2207 individuals, aged 1 -85 years (mean age, 31.4 ± 15.7 years), the prevalence of HBsAg was 9.8% (217/2207) after screening. Before screening, 6.8% (150/2207) of the participants claimed that they were vaccinated against HBV. Also, multivariate analysis revealed that HBV infection was significantly associated with age (21 -30 years) and vaccination status (P = 0.03; OR, 1.67; 95% CI, 1.04 to 2.69 and P = 0.003; OR, 5.69; 95% CI, 1.80 to 18.00, respectively). Among 217 HBsAg-positive cases, the prevalence of HBV markers was reported as follows: AbHBs (0.9%), HBeAg (6.0%), AbHBe (87.6%), and AbHBc (100.0%). Based on the findings, HCV was detected in 0.9% (2/217) of HBsAg-positive subjects. In this study, 628 out of 1990 HBsAg-negative subjects were vaccinated for three doses, resulting in a vaccination rate of 31.6%. Conclusions: The present study reported an HBsAg prevalence of 9.8% in the study population. This intervention could contribute to major vaccination coverage against HBV after screening. Therefore, raising awareness and development of screening campaigns on HBV can increase the vaccination coverage of the population. The findings also showed that absence of vaccination against HBV constitutes a high-risk factor for HBV infection.

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“…HBV prevalence among pregnant women is high in this region and varies between 6.2% and 16% with preponderance toward the upper end [76][77][78][79][80][81][82].…”

Section: Western Regionmentioning

confidence: 99%

Hepatitis B and C virus infections among pregnant women in Arab and African countries

Gasim

Murad

Adam

2013

J Infect Dev Ctries

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Introduction: The epidemiology of viral hepatitis during pregnancy is of paramount importance for health planners and program managers. Data on viral hepatitis during pregnancy are not readily available in many African and Arab countries. Both regions have their own unique geography, and comprise over 59 states with crossover and interaction of different cultures. Methodology: A systematic electronic search of the published literature was conducted and data on epidemiology and risk factors of maternal hepatitis B virus (HBV) infection and hepatitis C (HCV) infection in Arab and African countries were extracted from relevant studies. Results: The serology of hepatitis viruses varies greatly among these countries, with different viral genotype patterns. Such a variation in prevalence could be explained by the different risk factors involved. Sexual contact, perinatal infection, blood and its derivatives, hemodialysis, intravenous and percutaneous drug use, and occupational, habitual, and social behavior have been identified as risk factors for hepatitis transmission in various settings in these countries. Conclusions: Infection from hepatitis B and C viruses imposes major socioeconomic and even political burdens on such young and dynamic societies. Thus strategies and clear policies of intervention are required to combat the consequences of hepatitis B and C at both the regional and national levels.

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Toxoplasma gondii, HCV, and HBV seroprevalence and co‐infection among HIV‐positive and ‐negative pregnant women in Burkina Faso

Cited by 92 publications

References 13 publications

Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

World Hepatitis Day in Burkina Faso, 2016: Awareness, Screening, Identification of HBV Markers, HBV/HCV Coinfection, and Vaccination

Hepatitis B and C virus infections among pregnant women in Arab and African countries

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