Toxoplasma gondii-Associated Bilateral Panuveitis and Encephalitis after Bone Marrow Transplantation

Papazoglou, Anthia; Zweifel, Sandrine; Barthelmes, Daniel; Al-Sheikh, Mayss; Boeni, Christian

doi:10.1055/s-0043-121562

Cited by 1 publication

(1 citation statement)

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“…In addition, humans can be infected through consumption of food or water contaminated with sporulated T. gondii oocysts [22], and vertical transmission during pregnancy from an infected mother to her fetus [3]. Toxoplasma gondii infection in healthy individuals is usually asymptomatic or only shows self-limiting flu-like disease, but blindness and intellectual disability can be caused in congenitally infected children and serious complications in immunocompromized patients, such as AIDS, cancer, and transplant patients [1,15,21]. Children and young adults can also develop toxoplasmic chorioretinitis, which is a common manifestation of congenital or acute infection [20].…”

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confidence: 99%

Seroprevalence and risk factors of Toxoplasma gondii infection in primary school children in Henan province, central China

Wang

Yao

et al. 2020

Parasite

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Toxoplasma gondii is an obligate intracellular protozoan parasite with global distribution. However, data on T. gondii infection among children in primary school in Henan province, central China were lacking. In this study, 2451 serum samples of primary school children in this province were collected from September 2015 to October 2018 and evaluated for T. gondii antibodies using an enzyme-linked immunosorbent assay (ELISA). The overall seroprevalence was 9.51% (233/2451), of which 7.59% (186/2451) showed IgG positivity, 0.73% (18/2451) IgM and 1.18% (29/2451) both. The main risk factors related to T. gondii infections were the age of children, residence area, contact with cats, and exposure to soil. Moreover, hand washing before eating was considered a protective factor. Seroprevalence of T. gondii infection among the study population was common, emphasizing the need to prevent and control this infection. This is the first report of T. gondii seroprevalence in primary school children in Henan province, central China.

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