Seroprevalence and risk factors of <i>Toxoplasma gondii</i> infection in primary school children in Henan province, central China

Wang, Shuai; Yao, Zhijun; Li, Haoran; Li, Pengju; Wang, Dong; Zhang, Haizhu; Xie, Qing; Zhang, Zhenchao; Li, Xiangrui

doi:10.1051/parasite/2020018

Cited by 10 publications

(7 citation statements)

References 20 publications

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“…There is still no clear pathological evidence to understanding the vertical transmission of T. gondii infection and the possible mechanism for LBW in newborn babies. Eating raw or insufficiently cooked meat, improper hygiene practices, such as handwashing after handling raw meat, vegetables or fruits, and contact with domestic pets are the major paths of T. gondii transmission [ 37 , 38 ]. Conversely, the risk of LBW is multifactorial, including maternal host and behavioral factors, several sociodemographic factors, and certain environmental exposures [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Toxoplasma gondii Infection Is Associated with Low Birth Weight: Findings from an Observational Study among Rural Bangladeshi Women

et al. 2022

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Gestational Toxoplasma gondii (T. gondii) infection may cause substantial adverse effects on developing fetuses, newborns and also mothers. This study aims to estimate the seroprevalence of T. gondii among rural Bangladeshi pregnant women and determine the risk of a low birth weight (LBW). We followed a longitudinal design where 208 pregnant women were followed until the birth of their infants. Levels of IgG and IgM of T. gondii were assessed using chemiluminescent immunoassay. Modified Poisson regression was used to estimate crude and adjusted associations and multiple regression analysis was performed to understand the confounding and modifying effects of the variables. Thirty-nine (19%) children were born with LBW, among whom 15 (39%) mothers were positive for T. gondii IgG during pregnancy. After adjusting for several confounders and modifiers, pregnant women with T. gondii IgG or IgM seropositivity were significantly associated with LBW of infants (aRR: 2.00, 95% CI: 1.17–3.42). The strength of this association increased after adjusting for maternal education (aRR: 4.88, 95% CI: 1.74–13.69). The final model had an AROC of 0.84 with a sensitivity of 36% and specificity of 97%. Although causality is yet to be established, the study observed an association between T. gondii infection during pregnancy among rural Bangladeshi women and LBW of newborns.

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Section: Discussionmentioning

confidence: 99%

Toxoplasma gondii Infection Is Associated with Low Birth Weight: Findings from an Observational Study among Rural Bangladeshi Women

et al. 2022

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“…Blood samples were collected from 2451 primary school children in four cities of Henan province, as previously described [31]. The same sera were used in both studies.…”

Section: Study Site and Sample Collectionmentioning

confidence: 99%

Toxocara infection: seroprevalence and associated risk factors among primary school children in central China

Wang

Yao

et al. 2020

Parasite

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Toxocariasis is a zoonotic disease that poses a threat to public health worldwide. In the present study, we investigated the seroprevalence of Toxocara infection among primary school children in Henan province, central China, which was previously unknown. Sera from 2451 primary school children were collected from September 2015 to October 2018, and evaluated for anti-Toxocara antibodies by enzyme-linked immunosorbent assay (ELISA). The overall seroprevalence of Toxocara infection was 5.14% (126/2451). The main risk factors related to Toxocara infection identified in this study were the age of children, residence area of children, contact with cats or dogs, and exposure to soil. Hand washing before eating was considered to be a protective factor. These findings demonstrate that Toxocara infection is relatively common among primary school children in Henan province.

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“…This might be due to the different methods used in our study (MAT vs ELISA). A study conducted in Henan province (China) using ELISA indicated that the overall seroprevalence of T. gondii in primary school children was 9.51% [14]. Furthermore, students in SYAU are enrolled from all provinces around China, whereas students participating in our study are mainly from Anhui province.…”

Section: Discussionmentioning

confidence: 98%

Potential linkage betweenToxoplasma gondiiInfection and physical education scores of College Students

Zhi-jin

Jin

et al. 2020

Preprint

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Objective Toxoplasma gondii is a worldwide protozoan parasite that could infect virtually all warm-blooded animals, including humans. Our study aimed to investigate the prevalence of T. gondii infection in college students at Anhui province, China. Moreover, growing studies demonstrated the association between T. gondii infection and host behavioral changes. We also studied the linkage between T. gondii and scores of college students. Methods 2704 serum samples of medical school students attending physical education lessons were collected from September 2017 to September 2019 and evaluated for T. gondii IgG antibodies using an enzyme-linked immunosorbent assay (ELISA). We also analysed PE scores of T. gondii infected students and T. gondii uninfected students. Results The overall seroprevalence of T. gondii was 11.5%. The main risk factors related to T. gondii infections were cat in the household and gardening or agriculture activity. Furthermore, in basketball group and football group, scores of T. gondii seropositive students were significantly higher than that of seronegative students , while in other sports there is no difference between scores of T. gondii infected students and T. gondii uninfected students. Conclusion This is the first report of T. gondii seroprevalence in college students in Anhui province, China.

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Seroprevalence and risk factors of Toxoplasma gondii infection in primary school children in Henan province, central China

Cited by 10 publications

References 20 publications

Toxoplasma gondii Infection Is Associated with Low Birth Weight: Findings from an Observational Study among Rural Bangladeshi Women

Toxoplasma gondii Infection Is Associated with Low Birth Weight: Findings from an Observational Study among Rural Bangladeshi Women

Toxocara infection: seroprevalence and associated risk factors among primary school children in central China

Potential linkage betweenToxoplasma gondiiInfection and physical education scores of College Students

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