“…The method for the preclinical safety assessment of 6′‐SL (two in vitro genotoxicity tests and a 90‐day oral toxicity study) is similar to that used for other HiMOs, such as 3′‐sialyllactose sodium salt (3′‐SL) (Phipps et al, , accepted manuscript), LNnT (Coulet et al, ), 2′‐FL (Coulet et al, ), lacto‐ N ‐tetraose (Phipps, Baldwin, Lynch, Stannard, et al, ) and 2′‐FL/DFL (Phipps, Baldwin, Lynch, Flaxmer, et al, ). The in vitro assays represent the standard genotoxicity test battery covering gene mutations and chromosome aberrations using the minimum recommended number of tests (EFSA, ) and the 90‐day oral toxicity study was conducted to assess the potential subchronic toxicity of not only 6′‐SL itself, but of ‘other carbohydrates' within the final product (see Table ).…”