Toxicological evaluation of carbamazepine active pharmaceutical ingredient with Lepidium sativum, Daphnia magna and Vibrio fischeri toxicity test methods

Tongur, Süheyla; Yildiz, Sevil

doi:10.5004/dwt.2020.25969

Cited by 9 publications

(3 citation statements)

References 19 publications

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“…By utilizing these compounds to craft functional nanocomposite hydrogels, cutting-edge advancements in this area of research are literally changing our world for the better. 12 …”

Section: Introductionmentioning

confidence: 99%

“…By utilizing these compounds to cra functional nanocomposite hydrogels, cutting-edge advancements in this area of research are literally changing our world for the better. 12 Discover why Sodium Alginate (SA) is an extraordinary natural polymer with a wealth of advantages. From being widely available and biodegradable to its affordable cost and simple shaping potential, the fascinating molecule offers a number of carboxyl and hydroxyl groups along its backbonemaking it a widely studied material for improving the adsorption of pharmaceutical waste.…”

Section: Introductionmentioning

confidence: 99%

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Magnetic sodium alginate grafted with waste carbonaceous material for diclofenac sodium removal: optimization of operational parameters and process mechanism

et al. 2023

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“…By utilizing these compounds to craft functional nanocomposite hydrogels, cutting-edge advancements in this area of research are literally changing our world for the better. 12 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Magnetic sodium alginate grafted with waste carbonaceous material for diclofenac sodium removal: optimization of operational parameters and process mechanism

et al. 2023

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“…The sustainable discharge of wastewater without harming the environment aims to ensure the safety and protection of the aquatic ecosystems [27,28]. Pollutants in wastewater are generally complex and include pathogens and microorganisms and chemicals, such as those from personal care products, pharmaceuticals, polycyclic aromatic hydrocarbons, pesticides, phenolic compounds, steroids, and hormones [29,30]. Industrial pollutants are xenobiotic compounds that occur in the environment but are not routinely monitored, and their fate, behavior, and ecological toxic effects are not fully understood [31].…”

Section: Discussionmentioning

confidence: 99%

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

Tongur,

Atmaca

2023

Sustainability

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Wastewater ingredients present risks to the environment and can cause health problems. The aim of this study was to identify the toxicological effects of influent and effluent wastewater from Konya Urban Wastewater Treatment Plant (KU WWTP) and Konya Organized Industrial Zone Wastewater Treatment Plant (KOI WWTP). Three different trophic level toxicity tests were conducted to determine the possible harmful effects of wastewater on the environment. The base toxic unit values of the Lepidium sativum toxicity test for the inlet and outlet samples of KU WWTP were found to be 1.43 and 1.10, respectively. Both values classified the analyzed wastewater into the “toxic” category. Wastewater entering the KU wastewater treatment facility was classified as “toxic” for the presence of toxic substances according to the Vibrio fischeri toxicity testing. Influent samples from the KOI wastewater treatment plant were classified as “toxic” with the Vibrio fischeri toxicity test. In addition, based on the fish bioassay value (TDF), wastewater from the KOI treatment facility was also classified as “toxic”. It was concluded that increased chemical oxygen demand and concentrations of total nitrogen and phosphorus and of certain heavy metals above the limits played a decisive role in classifying the samples as “toxic”. The results of this study suggest that all three tests have the potential to assess wastewater toxicity and that changes in wastewater properties may result in differences in test sensitivity.

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Advanced methods for treating gemfibrozil and carbamazepine in wastewater: a review

Sivanesan,

Rameshwar,

Sivaprakash

et al. 2024

Environ Chem Lett

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The contamination of ecosystems by pharmaceuticals and personal care products represents a significant threat to public health, necessitating innovative approaches to clean wastewater before release into aquatic environments. Here, we review the emerging strategies and methods for the remediation of gemfibrozil and carbamazepine, emphasizing toxicological impacts, advanced oxidation processes, membrane-based removal techniques, and the underlying mechanisms driving these removal processes. We found that engineered composites with strong electron transfer capabilities can enhance the removal efficiency as they boost the generation of highly oxidative radicals. For instance, a nano zero-valent ion incorporated carbon–nitrogen composite removes 100% of gemfibrozil within 60 min. Similarly, a ruthenium perovskite-based heterogeneous catalyst achieved 100% elimination of carbamazepine in 7.5 min.

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Toxicological evaluation of carbamazepine active pharmaceutical ingredient with Lepidium sativum, Daphnia magna and Vibrio fischeri toxicity test methods

Cited by 9 publications

References 19 publications

Magnetic sodium alginate grafted with waste carbonaceous material for diclofenac sodium removal: optimization of operational parameters and process mechanism

Magnetic sodium alginate grafted with waste carbonaceous material for diclofenac sodium removal: optimization of operational parameters and process mechanism

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

Advanced methods for treating gemfibrozil and carbamazepine in wastewater: a review

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