Toxicological evaluation of Aridan,tetrapleura tetraptera(Mimosaceae), a molluscicide

Awe, S. O.; Adewunmi, C. O.; Iranloye, T. A.; Ojewole, John A. O.; Olubunmi, P. A.; Becker, W.

doi:10.1080/02772249509358226

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…It was clearer that field testing of Aridan in schistosomiasis control was more justifiable. Awe et al (1995).…”

Section: Control Of Schistosomiasis and Fascioliasismentioning

confidence: 99%

Tetrapleura tetraptera: Molluscicidal activity and chemical constituents

Aladesanmi

2007

Afr. J. Trad. Compl. Alt. Med.

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Tetrapleura tetraptera (Schumach. And Thonn) Taub, Mimosaceae, commonly known as Aridan (fruit), A single stemmed, robust, perennial tree of about 30m.It has a grey/brown, smooth/rough bark with glabrous yound branchlets. The flower is yellow/pink and racemes white the fruit has dark brown, four winged pods 12-25 x 3.5-6.5cm.It is generally found in the lowland forest of tropical Africa. The fruit consists of a fleshy pulp with small, brownish-black seeds. The fruit possesses a fragrants, characteristically pungent aromatic odour, which is attributed to its insect repellent property. It is used as spices and aroma (exotic tropical scents) and fish poisoning. It is one of the molluscicidal medicinal plants of Nigeria, also useful in the management of convulsions, leprosy, inflammation and/or rheumatoid pains. The documented biological and-or pharmacological activities are found to be molluscicidal, cardio-vascular, neuromuscular, hypotensive, anti-convulsant, molluscicidal, trypanocidal, hirudinicidal, schistomiasis control, anti-ulcerative, ectoxicity, anti-inflammatory, hypoglycaemic, anti-microbial, emulsifying property, birth control, food value and the control of intestinal parasites. Activity-guided fractionation of the methanol extract of the fruits of T. Tetraptera led to the isolation of a saponin glycoside with an oleanolic acid aglycone, a monodesmosidic diglycoside of the rare sapogenin 27-hydroxyolean-12 (13)-en-28-oic acid; echinocystic acid-3-0-sodium sulfate from the stembark, umbelliferone and ferulic acid from the leaves and branches respectively. Also isolated from the fruits were aridanin and three of its olean-12-en-28-oic acid derivatives. All the compounds isolated either from the fruits or other parts were found to exhibit strong molluscicidal properties against the schistosomiasis-transmitting snails Biomphalaria glabrata.

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“…It was clearer that field testing of Aridan in schistosomiasis control was more justifiable. Awe et al (1995).…”

Section: Control Of Schistosomiasis and Fascioliasismentioning

confidence: 99%

Tetrapleura tetraptera: Molluscicidal activity and chemical constituents

Aladesanmi

2007

Afr. J. Trad. Compl. Alt. Med.

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Phytochemical composition, bioactive properties, and toxicological profile of Tetrapleura tetraptera

Anyamele

Onwuegbuchu

Ugbogu

et al. 2023

Bioorganic Chemistry

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Evaluation of Valuation of Toxicity Profile of an Alkaloidal Fraction of the Stem Bark ofPicralima nitida(Fam. Apocynaceae)

Fakeye

Awe

Odelola

et al. 2004

Journal of Herbal Pharmacotherapy

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Dermal and acute toxicity evaluation of the basic alkaloidal fraction of the stem bark of Picralima nitida, which has been shown to have pronounced activity against causative organisms of dermatomycosis in man, was carried out in animals. Acute intraperitoneal toxicity tests showed a dose-dependent toxicity. There was inflammation and necrosis of liver hepatocytes accompanied by reduction in neutrophilic count and a corresponding increase in lymphocytic count. There was no sign of reddening or irritation when applied into the eye conjunctiva. Dermal tests also showed that the fraction caused no sensitization, inflammation or death in the animal models used.

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Toxicological evaluation of Aridan,tetrapleura tetraptera(Mimosaceae), a molluscicide

Cited by 3 publications

References 10 publications

<i>Tetrapleura tetraptera</i>: Molluscicidal activity and chemical constituents

<i>Tetrapleura tetraptera</i>: Molluscicidal activity and chemical constituents

Phytochemical composition, bioactive properties, and toxicological profile of Tetrapleura tetraptera

Evaluation of Valuation of Toxicity Profile of an Alkaloidal Fraction of the Stem Bark ofPicralima nitida(Fam. Apocynaceae)

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