Toxicity of Sanguinaria canadensis L. as Compared to Aloe vera L. against Brine Shrimp (Artemia salina) Using the Probit Methodology

Abstract

Toxicity study of Sanguinaria canadensis L. was determined as compared to Aloe vera (L.) Burm. f. against brine shrimp (Artemia salina). Upon statistical analysis of obtained toxicity bioassay data through the method of probits, LC50 of Sanguinaria canadensis was estimated as 0.021 mg/ml, with (95% C.I : 0.0091-0.0485) whereas Aloe vera was found to be almost non-toxic showing relatively higher LC50 that is, 180783.7 mg/ml.These results show that Aloe vera that is being used widely as an herbal medicine throughout the world, could be used safely for other various expected purposes for instance IPM etc. where the excessive amount is anticipated to drain into the sea ecosystem ultimately.

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

“…The plant extract and compounds that could be considered toxic (LC 50 = 10–100 μ g/ml) include the following: the ethyl acetate extracts of Monstera deliciosa leaves [ 85 ], the ethanol extract of Solanum americanum fruits [ 87 ], the ethanol extract of Scoparia dulcis aerial parts [ 76 ], the methanol extract of Enterolobium cyclocarpum leaves [ 88 ], the ethanol extract of Pimenta dioica leaves [ 89 ], and the hydroalcoholic extract of Sanguinaria canadensis whole plant [ 90 ]. None of the plant extracts or compounds included in this review were considered highly toxic (LC 50 < 10 μ g/ml).…”