Toxicity evaluation of barium ferrite nanoparticles in bacteria, yeast and nematode

Alvino, Lilibette; Pacheco-Herrero, Mar; López‐Lorente, Ángela I.; Quiñones, Zahíra; Cárdenas, Soledad; González-Sánchez, Zaira Isabel

doi:10.1016/j.chemosphere.2020.126786

Cited by 19 publications

(6 citation statements)

References 59 publications

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“…In another study, the effects of barium ferrite nanoparticles on bacteria, nematode, and yeast were investigated. They exhibited that BaFe nanoparticles at a concentration of 500 and 300 mg/mL had anti-worm and antibacterial activities against Staphylococcus aureus and Caenorhabditis elegans, respectively; however, these nanoparticles did not show antiyeast activity against Candida albicans [5].…”

Section: Discussionmentioning

confidence: 99%

Leishmanicidal activities of biosynthesized BaCO3 (witherite) nanoparticles and their biocompatibility with macrophages

Hashemi

Alijani

Mohammadi

et al. 2021

Bioprocess Biosyst Eng

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The aim of this study was cost-effective and greener synthesis of barium carbonate (BaCO 3 or witherite) nanoparticles with economic importance, and to evaluate their therapeutic potentials and biocompatibility with immune cells. Barium carbonate nanoparticles were biosynthesized using black elderberry extract in one step with non-toxic precursors and simple laboratory conditions; their morphologies and specific structures were analyzed using field emission scanning electron microscopy with energy dispersive X-ray spectroscopy (FESEM-EDX). The therapeutic capabilities of these nanoparticles on the immune cells of murine macrophages J774 and promastigotes Leishmania tropica were evaluated. BaCO 3 nanoparticles with IC 50 = 46.6 µg/ mL were more effective than negative control and glucantium (positive control) in reducing promastigotes (P < 0.01). Additionally, these nanoparticles with a high value of cytotoxicity concentration 50% (CC 50 ) were less toxic to macrophage cells than glucantime; however, they were significantly different at high concentrations compared to the negative control.

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Section: Discussionmentioning

confidence: 99%

Leishmanicidal activities of biosynthesized BaCO3 (witherite) nanoparticles and their biocompatibility with macrophages

Hashemi

Alijani

Mohammadi

et al. 2021

Bioprocess Biosyst Eng

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“…Cobalt Ferrite nanoparticles are obviously utilized for biomedical implementations imputing their ability to combat various human infections. The ultra-fine size nature of these nano-ferrites as well as their high specific surface area makes them effective against harmful microorganisms [29]. The antifungal influence of Barium nano-ferrite particles has been precisely investigated as illuminated in Figure 9.…”

Section: Anti-fungi Applicationsmentioning

confidence: 99%

“…Figure 9.Growth of Candida albicans treated with different concentrations of barium ferrite nanoparticles over control[29].…”

mentioning

confidence: 99%

Applications of Nano-Ferrites in Medicine

Ibrahim Ghoneim

2024

Applications of Ferrites

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Nano-ferrites are elegant and smart nanoparticles. Biomedical implementations of nano-ferrites include cell signaling, hyperthermia, magnetic resonance imaging (MRI), nanorobots, drug delivery, anti-cancer function, anti-fungi, anti-bacteria, biosensors, brain stimulation, wound healing, etc. Nano-ferrites showed anticancer features towards various types of cancer cells, such as breast cancer. They have been used for drug delivery as well as drug release. Magnetic hyperthermia is a successful approach in cancer treatment, where nano-ferrites have been used under the influence of external magnetic fields. Nano-ferrites are used as magnetic resonance imaging (MRI) contrast agents. Furthermore, nano-ferrites have been involved in the magnetic nanorobots and biosensors industries. Superparamagnetic nanocrystals including manganese nano-ferrites have been utilized in the activation of thermos-sensitive transient receptor potential vanilloid 1 (TRPV1) channels to attain further brain stimulation. The chemo-genetic modulation of targeted neural circuits using superparamagnetic nano-ferrite particles provides a novel strategy for brain stimulation so as to investigate brain functions and neurological diseases. Moreover, they have antibacterial and antifungal activity against several types of bacteria and fungi, such as E. coli and Candida albicans. Pr6O11/Fe2O3/GO@PCL film nanocomposites have been used in skin wound healing treatment; thence, these smart new nanocomposites could be utilized in the advancement of wound healing applications.

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“…A key step in the synthesis of nanoparticles is the reduction of metal ions, which may be accomplished by algae. Barium nanoparticles are renowned for their inhibitory effect on a wide range of bacteria and fungi [1][2][3][4]. Among these, BaONPs find diverse medical applications, including their integration into topical ointments and lotions as ionized compounds to combat infections [5].…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Spirogyra-hyalina-Mediated Barium Oxide Nanoparticles (BaONPs): Synthesis and Applications

Abdullah,

Rahman,

Faisal

et al. 2023

Molecules

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This research aims to biosynthesize Barium oxide nanoparticles (BaONPs) for biomedical applications, using Spirogyra hyalina as a stabilizing and reducing agent. UV–visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), energy-dispersive X-ray, X-ray diffraction (XRD), and scanning electron microscopy (SEM) were used to physiochemically characterize the barium oxide nanoparticles, while antibacterial, minimum inhibitory concentration, antifungal, free radicle scavenging, and anti-inflammatory assay were performed to assess the therapeutic potential of the synthesized BaONPs. Fourier transform infrared spectroscopy revealed bands at 615 and 692 cm−1 that corresponded to the formation of BaONPs. Scanning electron microscopy revealed the spherical and flower-shaped morphology of BaONPs having an average diameter of 64.01 ± 2.0 nm. Both Gram-positive and Gram-negative bacterial growth was halted by the barium nanoparticles, demonstrating their efficacy up to 19.12 ± 0.31 mm against E. coli, 18.83 ± 0.44 mm against Klebsiella pneumoniae, 17.31 ± 0.59 mm against P. aeruginosa, 16.56 ± 0.37 mm against S. aureus, and 15.75 ± 0.38 mm against S. epidermidis, respectively. The minimum inhibitory concentration was 9.0, 6.3, 5.5, 4.5, and 2.0 µg/mL for S. aureus, Klebsiella pneumoniae, S. epidermidis, P. aeruginosa, and E. coli, respectively. BaONPs were not that effective against fungal strains such as Rhizoctonia solani, Fusarium solani, and Fusarium proliferatum. The BaONPs exhibited potent anti-inflammatory and antioxidant activity through inhibiting cyclooxygenases type 1 (43.12 ± 1.21%) and 2 (41.23 ± 1.56%), and DPPH free radicles up to 43.52 ± 0.29% at 400 µg/mL. In conclusion, the biomolecules derived from Spirogyra hyalina have demonstrated remarkable ability to generate stable nanoparticles, offering promising prospects for their utilization as therapeutic agents and coating materials in various biomedical applications.

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Toxicity evaluation of barium ferrite nanoparticles in bacteria, yeast and nematode

Cited by 19 publications

References 59 publications

Leishmanicidal activities of biosynthesized BaCO3 (witherite) nanoparticles and their biocompatibility with macrophages

Leishmanicidal activities of biosynthesized BaCO3 (witherite) nanoparticles and their biocompatibility with macrophages

Applications of Nano-Ferrites in Medicine

Multifunctional Spirogyra-hyalina-Mediated Barium Oxide Nanoparticles (BaONPs): Synthesis and Applications

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