Toxicity‐Attenuated Glycol Chitosan Adhesive Inspired by Mussel Adhesion Mechanisms

Abstract

COMMUNICATION 1900275 (1 of 8)

Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications

“…In another study, chitosan modified with both catechol and ethylene glycol demonstrated hemostatic properties with a reduced immune response associated with catechol-modified chitosan. 165 However, glycol modification did not significantly improve the adhesive and hemostatic properties of the hydrogels when compared with the unmodified catechol-chitosan hydrogels. 148,165 In one interesting design, the surface of a needle was coated with a thin homogenous film of the partially oxidized catechol-functionalized chitosan.…”

“…165 However, glycol modification did not significantly improve the adhesive and hemostatic properties of the hydrogels when compared with the unmodified catechol-chitosan hydrogels. 148,165 In one interesting design, the surface of a needle was coated with a thin homogenous film of the partially oxidized catechol-functionalized chitosan. 166 The film thickness was around 20-26 μm depending on the needle gauge.…”

“…166,199,200 Chitosan has attracted considerable attention for hemostatic applications owing to its biocompatibility, biodegradability, and hemostatic activity through effective induction of platelet aggregation and adhesion at the injury site. 165,201,202 Therefore, various versions of catechol-functionalized chitosan have been reported as hemostatic agents.…”

Research Progress of Chitosan-Based Biomimetic Materials

“…The results showed that glycol CS-C significantly attenuated the immune response. However, the tissue adhesion and hemostatic ability of glycol CS-C were not dramatically improved, and it was speculated that the finding was likely due to the antibiofouling effect of the ethylene glycol group and the reduction of immune cell adhesion [ 35 ]. Although significant progress has been made in bioelectronics research in recent years, it is still challenging for self-adhesive bioelectronics to adhere to human tissues and achieve signal detection without external aids.…”

Plant Polyphenol‐Inspired Crosslinking Strategy toward High Bonding Strength and Mildew Resistance for Soy Protein Adhesives

“…[3] Biomass-based nonformaldehyde adhesive substitutes with good bonding properties have been widely applied for the wood panel industry. [4] Among the many biomass-based raw materials such as lignin, [5] tannin, [6] protein, [7] starch, [8] and chitosan, [9] soy protein has become an ideal material for preparing wood adhesives due to its abundant resources, renewability, and low price; however, the low bonding strength, poor water, and mold resistance have limited its applications. [10][11][12]13] In order to enhance the performance defects of soy protein adhesives, a series of modification strategies have been used, such as the use of protein denaturation techniques, chemical crosslinking, organic or inorganic blending, and biomimetic design.…”