Toxic epidermal necrolysis following measles vaccination

Shoss, R. G.

doi:10.1001/archderm.110.5.766

Cited by 13 publications

(6 citation statements)

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“…The occurrence of bullous skin diseases after immunization has been described previously, e.g. toxic epidermal necrolysis following measles vaccination 9 …”

Section: Discussionmentioning

confidence: 78%

Paraneoplastic pemphigus with fatal pulmonary involvement in a woman with a mesenteric Castleman tumour

Wolff

Kunte

Messer

et al. 1999

British Journal of Dermatology

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A 42-year-old woman presented with oral and labial erosions, conjunctivitis, facial rash and lichenoid erythematous papules on the trunk. Paraneoplastic pemphigus (PNP) was suspected, and a search for a neoplasm revealed an intra-abdominal Castleman tumour sized 7 x 5 x 6 cm. After removal of the Castleman tumour, the skin and mucosal inflammation gradually subsided over the next 12 months. However, due to irreversible pulmonary involvement the patient died of intractable respiratory distress 2 years after the onset of the disease. Systemic corticosteroids, azathioprine, cyclophosphamide, high-dose intravenous immunoglobulins and thalidomide were ineffective. The diagnosis of PNP was confirmed by keratinocyte antigen immunoprecipitation with the patient's serum.

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“…The occurrence of bullous skin diseases after immunization has been described previously, e.g. toxic epidermal necrolysis following measles vaccination 9 …”

Section: Discussionmentioning

confidence: 78%

Paraneoplastic pemphigus with fatal pulmonary involvement in a woman with a mesenteric Castleman tumour

Wolff

Kunte

Messer

et al. 1999

British Journal of Dermatology

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“…Interestingly, the initial morphologies of TEN following vaccination appear to fall into three general categories: macular, vesicular, and targetoid (EM-like). A macular rash, often dusky red in color, was by far the most common initial morphology of TEN post-vaccination, as would be expected for the majority of cases of TEN related to other etiologies [8,22,23]. Vesicles were the presenting morphology in 4 cases; notably, all occurred after administration of a measles-containing vaccine [10,[23][24][25].…”

Section: Resultsmentioning

confidence: 99%

Vaccine-induced toxic epidermal necrolysis: A case and systematic review

Chahal¹,

Aleshin²,

Turegano³

et al. 2018

DOJ

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“…Immunizations are rare, but very' important aetiological factors in non-drug induced TEN. To the best of our knowledge, the following immunizations were proven causes of TEN: smallpox [3], measles [4], diphtheria-pertussistetanus [S], poliomyelitis, inff uenza [6] and BCG [7].…”

Section: Introductionmentioning

confidence: 99%

Toxic epidermal necrolysis following morbilli-parotitis-rubella vaccination

Dobrosavljevic

Milinković

Nikolić

1999

Journal of the European Academy of Dermatology and Venereology

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We present the first reported case of toxic epidermal necrolysis (TEN) caused by morbilli-parotitis-rubella (MPR) vaccine. A 13-year-old girl developed TEN 7 days after she received live, attenuated, triple MPR vaccine. The history of drug intake and any illness was negative. At admission the patient was acutely ill with high fever. The whole body was erythematous. The epidermis was wrinkled and the Nikolsky sign was positive. Numerous erosions were present on the lips and genital region. On the seventh day of illness, the eruption involved 80% of the skin. Systemic corticosteroid therapy was not employed. The skin and mucosal defects completely epithelized by the end of the third week of illness. Mild keratoconjunctivitis sicca remained because of permanent cup cell damage.

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Toxic epidermal necrolysis following measles vaccination

Cited by 13 publications

References 0 publications

Paraneoplastic pemphigus with fatal pulmonary involvement in a woman with a mesenteric Castleman tumour

Paraneoplastic pemphigus with fatal pulmonary involvement in a woman with a mesenteric Castleman tumour

Vaccine-induced toxic epidermal necrolysis: A case and systematic review

Toxic epidermal necrolysis following morbilli-parotitis-rubella vaccination

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