2022
DOI: 10.3390/jpm12081275
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Towards Treatable Traits for Pulmonary Fibrosis

Abstract: Interstitial lung diseases (ILD) are a heterogeneous group of disorders, of which many have the potential to lead to progressive pulmonary fibrosis. A distinction is usually made between primarily inflammatory ILD and primarily fibrotic ILD. As recent studies show that anti-fibrotic drugs can be beneficial in patients with primarily inflammatory ILD that is characterized by progressive pulmonary fibrosis, treatment decisions have become more complicated. In this perspective, we propose that the ‘treatable trai… Show more

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Cited by 3 publications
(2 citation statements)
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References 133 publications
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“…ILDs are a heterogeneous group of lung disorders; several may lead to progressive pulmonary fibrosis 37 . There is a higher ILD prevalence in women related to connective tissue diseases and hypersensitivity pneumonitis (HP); home environmental antigens are mostly responsible for this gender-difference.…”
Section: Interstitial Lung Diseasesmentioning
confidence: 99%
See 1 more Smart Citation
“…ILDs are a heterogeneous group of lung disorders; several may lead to progressive pulmonary fibrosis 37 . There is a higher ILD prevalence in women related to connective tissue diseases and hypersensitivity pneumonitis (HP); home environmental antigens are mostly responsible for this gender-difference.…”
Section: Interstitial Lung Diseasesmentioning
confidence: 99%
“…There is a higher ILD prevalence in women related to connective tissue diseases and hypersensitivity pneumonitis (HP); home environmental antigens are mostly responsible for this gender-difference. Because they can have extremely aggressive behavior, treatable traits for ILDs have been proposed 37 . Smoking is definitely one of them, being linked to more severe HP, worse survival in idiopathic pulmonary fibrosis, and other progressive ILDs.…”
Section: Interstitial Lung Diseasesmentioning
confidence: 99%