2023
DOI: 10.1038/s41526-023-00262-7
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Towards sustainable human space exploration—priorities for radiation research to quantify and mitigate radiation risks

Abstract: Human spaceflight is entering a new era of sustainable human space exploration. By 2030 humans will regularly fly to the Moon’s orbit, return to the Moon’s surface and preparations for crewed Mars missions will intensify. In planning these undertakings, several challenges will need to be addressed in order to ensure the safety of astronauts during their space travels. One of the important challenges to overcome, that could be a major showstopper of the space endeavor, is the exposure to the space radiation env… Show more

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Cited by 19 publications
(9 citation statements)
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References 48 publications
(52 reference statements)
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“…To date, also the discussions about the influence of age and gender as those about the importance of genetic predisposition on radiation effects are by no means concluded [24] . ESA roadmap for space radiation research includes spaceflight and ground-based experiments, as well as risk modelling studies [25] , [26] . Ground-based studies in space radiation protection in Europe are based at the GSI synchrotron in Darmstadt (Germany), able to accelerated heavy ions up to 1 GeV/n [27] .…”
Section: European Space Agency (Esa)mentioning
confidence: 99%
“…To date, also the discussions about the influence of age and gender as those about the importance of genetic predisposition on radiation effects are by no means concluded [24] . ESA roadmap for space radiation research includes spaceflight and ground-based experiments, as well as risk modelling studies [25] , [26] . Ground-based studies in space radiation protection in Europe are based at the GSI synchrotron in Darmstadt (Germany), able to accelerated heavy ions up to 1 GeV/n [27] .…”
Section: European Space Agency (Esa)mentioning
confidence: 99%
“…However, as astronauts venture further into space, the dose rate will increase to 110-300 mSv/year on the Moon and 130-260 mSv/year on Mars. Since solid tumor induction may occur at effective doses as low as 200 mSv (20) and radiation health effects for astronauts include but are not limited to accelerated aging of tissues, an increased risk of cardiovascular disease, cancer, and neurodegeneration (21,22), radiation countermeasures are needed to protect astronauts.…”
Section: Session I: Microphysiological Systems and Chip Technologiesmentioning
confidence: 99%
“…Therefore, predicting SEP events in advance provides the decision-makers and astronauts with adequate time to take action and reduce the risks. Space agencies need to accurately predict these rare events to reduce the risks and ensure the safety of their missions (Fogtman et al 2023).…”
Section: Introductionmentioning
confidence: 99%