Toward a new biology of social adversity

Boyce, W. Thomas; Sokolowski, Marla B.; Robinson, Gene E.

doi:10.1073/pnas.1121264109

Cited by 110 publications

(98 citation statements)

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“…A more recent focus within population sciences on how the broader environment "gets under the skin" suggests that this may be a key moment to look to the brain. Health psychologists have demonstrated that the broader environment becomes biologically embedded in the brain over the course of development (5,(13)(14)(15)(16)(17), but how does this yield observed variations within populations? Therefore, we argue that the critical juncture described for neuroscience research also poses an opportunity for population science research more broadly.…”

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confidence: 99%

What is a representative brain? Neuroscience meets population science

Falk

Hyde

Mitchell³

et al. 2013

Proc. Natl. Acad. Sci. U.S.A.

226

191

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The last decades of neuroscience research have produced immense progress in the methods available to understand brain structure and function. Social, cognitive, clinical, affective, economic, communication, and developmental neurosciences have begun to map the relationships between neuro-psychological processes and behavioral outcomes, yielding a new understanding of human behavior and promising interventions. However, a limitation of this fast moving research is that most findings are based on small samples of convenience. Furthermore, our understanding of individual differences may be distorted by unrepresentative samples, undermining findings regarding brain-behavior mechanisms. These limitations are issues that social demographers, epidemiologists, and other population scientists have tackled, with solutions that can be applied to neuroscience. By contrast, nearly all social science disciplines, including social demography, sociology, political science, economics, communication science, and psychology, make assumptions about processes that involve the brain, but have incorporated neural measures to differing, and often limited, degrees; many still treat the brain as a black box. In this article, we describe and promote a perspective-population neuroscience-that leverages interdisciplinary expertise to (i) emphasize the importance of sampling to more clearly define the relevant populations and sampling strategies needed when using neuroscience methods to address such questions; and (ii) deepen understanding of mechanisms within population science by providing insight regarding underlying neural mechanisms. Doing so will increase our confidence in the generalizability of the findings. We provide examples to illustrate the population neuroscience approach for specific types of research questions and discuss the potential for theoretical and applied advances from this approach across areas.neuroimaging | life course | statistics | survey methodology | physics Why Population Neuroscience? How do biology, social situations, and the broader environmental context interact to guide behavior, health, and development? This question is fundamental to most, if not all, social and behavioral sciences. We argue that to effectively address the many topics that stem from this larger question across disciplines, it is necessary to (i) bring a "population perspective" to neuroscience and (ii) leverage neuroscience tools within population sciences, which are subdisciplines of many fields, areas, and departments focused on documenting and understanding the dynamics of human populations, including outcomes such as health, well-being, behavior, etc.

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mentioning

confidence: 99%

What is a representative brain? Neuroscience meets population science

Falk

Hyde

Mitchell³

et al. 2013

Proc. Natl. Acad. Sci. U.S.A.

226

191

View full text Add to dashboard Cite

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“…118], включающей объединения спай-ков в виде "пачек", что отмечается как в поверхностных, так и глубоких слоях коры [122,123]. Пачечная активность генерируется посредством кон-туров с обратным связями -"neuronal circuits" [118]. Недавно описаны пред-полагаемые сложные схемы образования и функционирования "neuronal circuits" в коре больших полушарий [106, 109, 123, 124, 129.…”

Section: общее заключение с комментариями и прогнозамиunclassified

Russian Foundation for Basic Research: Bibliometric Analysis of Publishing Scientific Projects

Чиженкова¹

2017

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“…The relation of genetics and epigenetics with SES and neural development is a relatively unexplored yet important field for future endeavors (10). Strong genetic effects on neonatal MRI outcomes have been shown in twin studies (113).…”

Section: Ongoing and Future Researchmentioning

confidence: 99%

“…The literature is replete with reports of deleterious effects on developmental outcome, cognitive function, and school performance in young children (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Factors implicated as causative agents include poor nutrition, exposure to toxins, inadequate parenting, lack of cognitive stimulation, unstable social support, and genetics (13)(14)(15)(16)(17)(18).…”

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confidence: 99%