Toward a Neuroethology of Schizophrenia: Findings from the Crimean Project

Samokhvalov, Victor P.; Samokhvalova, Oxana E.

doi:10.1007/978-94-007-0831-0_6

Cited by 3 publications

(1 citation statement)

References 57 publications

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“…Отримано дані щодо стійких нейрокогнітивних розладів при шизо фре нії, ШАР і АР та наявність зв'язку нейрокогнітивного дефіциту зі зниженням рівня соціальної адаптації, стійкими проявами ворожості та особливостями захисної організації особистості при ендогенних психозах, зв'язків преморбідних особливостей з клінікою дебюту, невербальними особливостями соціально-комунікативної поведінки та ін. [2,[6][7][8]. Подальше вивчення та узагальнення даних щодо нейрокогнітивних порушень як складника патоперсонологічних трансформацій при ШАР та їх зв'язку з клініко-анамнестичними та медико-біологічними характеристиками (зокрема, вивчення впливу психофармакологічних втручань на структуру і вираженість нейрокогнітивного дефіциту) є потрібним задля реалізації мети створення системи диференціальної діагностики в межах кластера ендогенних психозів з епізодичним перебігом та протидії соціальній дезадаптації з використанням індивідуальних психофармакологічних та психокорекційних програм.…”

Section: Ye Khomitskyi Interrelation Of Clinical-anamnestic Medical-biological and Neurocognitive Characteristics Of Maladaptation In Remunclassified

Interrelation of clinical-anamnestic, medical-biological and neurocognitive characteristics of maladaptation in remission as a component of pathopersonological transformations in patients with schizoaffective disorder

Khomitskyi¹

2020

UVP

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The aim of the study was to study the interrelation between clinical, medical, biological and neurocognitive characteristics of maladaptation (as a component of pathopersonological transformations) in patients with schizoaffective disorder in remission. On the basis of the Regional Clinical Psychiatric Hospital (Zaporizhzhia, Ukraine) 102 persons with the established diagnosis of “schizoaffective disorder” were examined. Diagnosis was per formed according to the International ICD-10. The mandatory criteria for inclusion in the study were the presence of a condition of clinical remission with reduction of psychotic symptoms and the absence of severe somatic and neurological pathology, abuse of psychoactive substances. The main methods of the study were clinical psychopathological, psychodiagnostical, clinical-anamnestic and clinical-cathamnestic as well as medi cal and statistical analysis. The study established the presence and regularities of conjugation of clinical, medical, biological, and neurocognitive characteristics of maladaptation (as a component of pathopersonological transformations) in patients with schizoaffective disorder in remission. The structure of neurocognitive deficits in schizoaffective disorder in remission is related to the clinical type of the disease, the sex, the duration of the pathological process, and the characteristics of psychopharmacological treatment. The established regularities emphasize the importance of neurocognitive disorders in the structure of pathopersonological transformations and can be used in the formation of the system of diagnostic and treatment and rehabilitation measures to improve the quality of differential diagnosis and to carry out preventive and therapeutic rehabilitation measures to reduce the level of social maladaptation of patients with schizoaffective disorder. Keywords: schizoaffective disorder, clinic, neurocognition, social maladaptation, pathopersonalogical transformations

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Section: Ye Khomitskyi Interrelation Of Clinical-anamnestic Medical-biological and Neurocognitive Characteristics Of Maladaptation In Remunclassified

Interrelation of clinical-anamnestic, medical-biological and neurocognitive characteristics of maladaptation in remission as a component of pathopersonological transformations in patients with schizoaffective disorder

Khomitskyi¹

2020

UVP

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An algorithm for the diagnostic differentiation of schizoaffective disorder and other endogenous psychoses with episodic course (schizophrenia and affective disorders)

Khomitskyi

2020

Patologìâ

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Typology of Pathopersonological Transformations in Patients With Schizoaffective Disorder

Khomitskyi

2020

EUMJ

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The issue of diagnostics, treatment and social rehabilitation of patients with endogenous psychoses with episodic course remains one of the most urgent problems of psychiatry, which, despite the considerable advances of science and practice, has not found a definitive solution. Significant difficulties of nosological separation in the group of endogenous psychoses with episodic course and evaluation of the pathopersonological aspect of the clinic are related to schizoaffective disorder. The aim of the study was to establish a typology of pathopersonological transformations in patients with schizoaffective disorder based on the analysis of clinical-psychopathological, medical-psychological, clinical-ethological characteristics of remission. On the basis of “Regional Clinical Psychiatric Hospital” (Zaporizhzhіa) 102 persons with the established diagnosis of schizoaffective disorder were examined. The main methods of the study were clinical psycho-pathological, psychodiagnostic, patho-psychological, clinical-anamnestic, clinical-medical, social-medical and statistical analysis. As a result of the conducted research, on the basis of the analysis of clinical-psychopathological, medical-psychological, clinical-ethological characteristics of remission, the typology of pathopersonological transformations was established. The presence and prevalence of 4 main types of pathopersonological transformations in schizoaffective disorder (“affective-labile” (20.1 % of the contingent), “paranoid-dysthymic” (17.3 %), “hysteroid-agonistic” (25.9 %), “Neurocognitive-deficient” (16.9 %) and “mixed” (19.8 % of the contingent)), which differ in clinical-anamnestic, clinical-psychopathological, medical-psychological, neuropsychological and clinical-ethological characteristics and cause social (labor and family) maladjustment of varying degrees. The clinical-anamnestic, clinical-psychopathological, medical-psychological, neuropsychological and clinical-ethological features identified in the study can be used to determine the type of pathopersonological transformations and its severity in patients with schizoaffective disorder and, accordingly, quantitative characteristics of individually needed psychopharmacological, psychotherapeutic and social rehabilitation activities and evaluation of their effectiveness in dynamics.

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Toward a Neuroethology of Schizophrenia: Findings from the Crimean Project

Cited by 3 publications

References 57 publications

Interrelation of clinical-anamnestic, medical-biological and neurocognitive characteristics of maladaptation in remission as a component of pathopersonological transformations in patients with schizoaffective disorder

Interrelation of clinical-anamnestic, medical-biological and neurocognitive characteristics of maladaptation in remission as a component of pathopersonological transformations in patients with schizoaffective disorder

An algorithm for the diagnostic differentiation of schizoaffective disorder and other endogenous psychoses with episodic course (schizophrenia and affective disorders)

Typology of Pathopersonological Transformations in Patients With Schizoaffective Disorder

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