Totally laparoscopic liver resections for primary and metastatic cancer in the elderly: safety, feasibility and short-term outcomes

Spampinato, Marcello; Arvanitakis, Marianna; Puleo, Francesco; Mandalà, Lucio; Quarta, Giuseppe; Traisci, Donatella; Plaia, Antonella; Bartolomeo, Nicola; Baldazzi, Giànandrea; Cillo, Umberto

doi:10.1007/s00464-012-2687-4

Cited by 18 publications

(26 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yet clinical data on laparoscopic liver resection in comparison with open resection in the same setting are lacking. One recent study addressed the feasibility of laparoscopic approach for elderly patients, but their perioperative outcomes in relation to the conventional open approach were not determined . On the other hand, our study demonstrated some of the potential advantages of laparoscopic liver resections over the open approach for this category of patients.…”

Section: Discussionmentioning

confidence: 76%

Laparoscopic versus open liver resection for elderly patients with malignant liver tumors: A single‐center experience

Chan

Poon

Cheung

et al. 2014

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 76%

Laparoscopic versus open liver resection for elderly patients with malignant liver tumors: A single‐center experience

Chan

Poon

Cheung

et al. 2014

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

“…In support of this hypothesis, other reports demonstrated the safety of LLR for elderly. 33,34 Although these reports and the present study were smallscale case studies, our data adds important information regarding the application of LLR for elderly patients.…”

Section: Discussionmentioning

confidence: 77%

Surgical Outcomes of Laparoscopic Liver Resection in Elderly Patients

Uchida

Iwashita

Watanabe

et al. 2015

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

View full text Add to dashboard Cite

The life expectancy continues to gradually increase worldwide. Laparoscopic liver resection (LLR) was recently reported to be a relatively safe procedure for treatment of liver disease because of the development of new techniques and instruments. The aim of this study was to evaluate the surgical outcomes of elderly patients who underwent LLR. Of these 61 patients who underwent LLR in our institute from January 2010 through April 2014, 21 were aged 75 years and above (group E), and 40 were aged below 75 years (group NE). Patient characteristics were retrospectively analyzed between the 2 groups. The results showed that patient characteristics were similar between the 2 groups, although the incidence of hypertension was significantly greater among patients in group E. There were no significant differences in the incidence of postoperative complications or length of hospital stay between the 2 groups. In conclusion, LLR for elderly patients was a feasible procedure compared with nonelderly patients.

show abstract

“…After exclusion of duplicate or irrelevant references, 53 potentially relevant articles were retrieved. After detailed evaluation of these articles, 27 studies remained for assessment, including a total of 4769 elderly patients ≥70 years of age and 15 855 patients ≤70 years old ( n = 20 624) (Table ).…”

Section: Resultsmentioning

confidence: 99%

“…All of the 27 included studies were observational studies, with five prospective, 20 retrospective and two propensity‐matched studies . There were 17 studies which consisted of 50 or more patients in the elderly cohort, while the remaining had fewer than 50 elderly patient . The tumour type was HCC in 10 studies, CLM in nine studies and eight studies had liver resections for other or mixed tumour types …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Hepatic resection for malignant liver tumours in the elderly: a systematic review and meta‐analysis

Phan

et al. 2015

ANZ Journal of Surgery

View full text Add to dashboard Cite

Background: The number of elderly patients undergoing hepatic resection for surgical treatment of benign and malignant cancers is increasing. However, there is limited clinical data on the complications and long-term survival rates associated with liver surgery in the elderly patients (≥70 years) versus younger patients for malignant liver conditions. Methods: Six electronic databases were searched for original published studies comparing elderly (≥70) versus younger (<70) cohorts for malignant liver tumours. Data were extracted and analysed according to predefined clinical endpoints. Results: Twenty-seven comparative studies were identified, including 4769 elderly patients versus 15 855 younger patients (n = 20 624). There was significantly higher 30-day mortality in the elderly colorectal liver metastasis group (P < 0.00002) and significant difference between elderly and young in terms of overall survival (hazard ration (HR), 1.10; P = 0.02). However, there was no difference in disease-free survival (HR, 1.05; P = 0.27). Post-operative pneumonia, renal failure and infection were more frequent in the elderly group. Conclusions: Liver resection for malignant hepatic tumours in the elderly is associated with a greater 30-day mortality and overall mortality when compared with younger cohorts, but similar disease-free survival. Length of stay and transfusions were not significantly different while pneumonia, renal failure and infections were more frequent in the elderly group.

show abstract

Totally laparoscopic liver resections for primary and metastatic cancer in the elderly: safety, feasibility and short-term outcomes

Abstract: This retrospective comparative study shows that TLLR performed on elderly for liver neoplasm are feasible and safe and lead to short-term outcomes similar to those of younger patients.

Cited by 18 publications

References 18 publications

Laparoscopic versus open liver resection for elderly patients with malignant liver tumors: A single‐center experience

Laparoscopic versus open liver resection for elderly patients with malignant liver tumors: A single‐center experience

Surgical Outcomes of Laparoscopic Liver Resection in Elderly Patients

Hepatic resection for malignant liver tumours in the elderly: a systematic review and meta‐analysis

Contact Info

Product

Resources

About