“…Gibbons, Iselin and colleagues demonstrated excellent cancer control in patients who were followed for 20 years after RPP and showed that locally confined cancers can be safely removed with good long-term tumour-free survival using the perineal approach [Iselin et al 1999;Gibbons et al 1989]. Comploj and colleagues noted an overall biochemical progression-free survival of 86% [Comploj et al 2011].…”
Radical perineal prostatectomy is an alternative to the retropubic, robotic-assisted or the laparoscopic approach and it is one of the oldest surgical procedures for prostate cancer, but its use has declined over the past 30 years. The desire for lower morbidity, short hospital stay, and decreased costs has resulted in a renaissance of radical perineal prostatectomy. The combination of low morbidity, short hospital stay, and low economic costs brought to a renaissance of radical perineal prostatectomy.
“…Gibbons, Iselin and colleagues demonstrated excellent cancer control in patients who were followed for 20 years after RPP and showed that locally confined cancers can be safely removed with good long-term tumour-free survival using the perineal approach [Iselin et al 1999;Gibbons et al 1989]. Comploj and colleagues noted an overall biochemical progression-free survival of 86% [Comploj et al 2011].…”
Radical perineal prostatectomy is an alternative to the retropubic, robotic-assisted or the laparoscopic approach and it is one of the oldest surgical procedures for prostate cancer, but its use has declined over the past 30 years. The desire for lower morbidity, short hospital stay, and decreased costs has resulted in a renaissance of radical perineal prostatectomy. The combination of low morbidity, short hospital stay, and low economic costs brought to a renaissance of radical perineal prostatectomy.
“…3 Kaplan-MeierAnalyse des rezidivfreien Überlebens nach radikaler Prostatektomie stratifiziert nach dem Karzinomvolumen (n=1755, Hamburger Prostatakarzinomregister) nach 15 Jahren.Gibbons et al [24] berichteten nach einem Nachsorgeintervall von 15-35 Jahren von einer tumorspezifischen Überlebensrate von 82%.Als der am häu-figsten in der Literatur verwendete Parameter zur Festlegung des Therapieerfolgs der radikalen Prostatektomie hat sich das rezidivfreie Überleben -definiert durch einen PSA-Wert unterhalb der Nachweisgrenze und dem Fehlen eines klinischen Progresses -etabliert. Die rezidivfreien Überlebensraten 5 und 10 Jahre nach radikaler Prostatektomie sind hoch und liegen je nach untersuchtem Patientenkollektiv bei 77-83% [4,25].…”
Section: Ergebnisse Der Radikalen Prostatektomieunclassified
Radical prostatectomy represents the mainstay of therapy for clinically localized prostate cancer. The combination of diagnostic parameters such as PSA or biopsy Gleason grade in nomograms allows a safe prediction of pathologic stage and prognosis of the disease. Imaging techniques are useful in a subset of patients. International studies have proven a high cancer control rate of radical prostatectomy. A nerve-sparing modification of the operative technique does not compromise radicality of the procedure if patients are carefully selected. For this purpose simple and reliable algorithms are available.
“…Although a matter for many sometimes heated discussions, one must conclude that there are today no adequate studies that compare the effectiveness and side effects of these options [12,31,32,35,37,66,80]. Fortunately, both forms of treatment have an acceptable morbidity and most often patient prefer ence is -or should be -a dominant factor in selecting one form of treatment over another [74], The most appro priate role for the involved physician is to carefully explain all the risks and benefits of each option and then help the patient decide which therapy is the most accept able to him.…”
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