Total Phenolic Content and Antioxidant and Antibacterial Activities of <i>Pereskia bleo</i>

Johari, Mas Athira; Khong, Heng Yen

doi:10.1155/2019/7428593

Cited by 84 publications

(76 citation statements)

References 10 publications

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“…The antioxidant activity (DPPH) was strongest in methanolic extract compared to the other to extract. The antibacterial activity of these three extracts were measured and the MIC (225 µg/mL) were higher against Staphylococcus aureus and Streptococcus pyogenes compared to hexane (1800 µg/mL) [70]. Nevertheless, there are exceptions where non-polar extracts showed the strongest antioxidant activity as demonstrated by Prabhakar, et al [71].…”

Section: Discussionmentioning

confidence: 95%

“…Furthermore, ethanolic extract showed the strongest antioxidant activity against DPPH and ABTS free radicals. Moreover, a study by Johari and Khong [70] demonstrated that methanolic extract demonstrated highest TPC followed by chloroform and lastly hexane which indicate the decline in polarity level of the solvents. The antioxidant activity (DPPH) was strongest in methanolic extract compared to the other to extract.…”

Section: Discussionmentioning

confidence: 98%

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Streptomyces sp. Strain MUSC 125 from Mangrove Soil in Malaysia with Anti-MRSA, Anti-Biofilm and Antioxidant Activities

et al. 2020

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There is an urgent need to search for new antibiotics to counter the growing number of antibiotic-resistant bacterial strains, one of which is methicillin-resistant Staphylococcus aureus (MRSA). Herein, we report a Streptomyces sp. strain MUSC 125 from mangrove soil in Malaysia which was identified using 16S rRNA phylogenetic and phenotypic analysis. The methanolic extract of strain MUSC 125 showed anti-MRSA, anti-biofilm and antioxidant activities. Strain MUSC 125 was further screened for the presence of secondary metabolite biosynthetic genes. Our results indicated that both polyketide synthase (pks) gene clusters, pksI and pksII, were detected in strain MUSC 125 by PCR amplification. In addition, gas chromatography-mass spectroscopy (GC-MS) detected the presence of different chemicals in the methanolic extract. Based on the GC-MS analysis, eight known compounds were detected suggesting their contribution towards the anti-MRSA and anti-biofilm activities observed. Overall, the study bolsters the potential of strain MUSC 125 as a promising source of anti-MRSA and antibiofilm compounds and warrants further investigation.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 98%

Streptomyces sp. Strain MUSC 125 from Mangrove Soil in Malaysia with Anti-MRSA, Anti-Biofilm and Antioxidant Activities

et al. 2020

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“…Gallic acid was used as a standard for the calibration curve to determine the total phenolic concentration of the oleoresin extracts expressed in mg/L gallic acid equivalents. The total phenolic contents were calculated in triplicates using Equation (1).…”

Section: Total Phenolics Contentmentioning

confidence: 99%

“…In recent times there has been a renewed interest in the study of major phenolics content in medicinal plants. Evidence from traditional medicine practitioners confirmed that frequent consumption of these plants could mitigate many life-threatening diseases which is a safe alternative to the use of synthetic drugs [1,2]. It is pertinent to note that tropical regions are vastly enriched with varieties of medicinal plants with potential application in pharmaceutical and food industries [3].…”

Section: Introductionmentioning

confidence: 99%

Multi-step reflux extraction of bio-pharmaceutical phenolic bioactives from balsam apple (Momordica balsamina L.)

Olalere

Gan

2020

Journal of Taibah University for Science

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In this study, the impacts of parameter combinations on the response (total phenolic yield) were evaluated using the single experiments and two-level factorial design. The investigated parameters with their value range include; the microwave extraction time (1-5 min), power level (400-600 W), temperature (60-80°C), the solvent-feed ratio, SFR (8-12 mL/g) and solvent concentration (50-80%). The result of this investigation succinctly presented the solvent concentration as the highest contributing parameters, far above the Bonferroni limit (8.37517) and t-value limit (3.18245). However, the temperature, SFR and microwave duration provided insignificant contribution to the response settings. The result of the spectrometry chromatographic analysis identified 22 phenolics compounds from the extracts which invariably revealed their potential biological functions. The study therefore adequately elucidated the contributing factor in the microwave recovery of total phenolic constituents from the M. balsamina leaves with potential use as scale-up parameters in drug applications.

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“…They are made up of hydroxylated aromatic rings attached to the phenyl or aryl group compound (Balasundram et al, 2006). Phenolic compounds are the most abundant structures in plants that possess antioxidant activity through their redox reaction (Johari and Khong, 2019). Total phenolic content is an analysis to measure the amount of phenolic content in one sample.…”

Section: Total Phenolic Content Of Sugarcane Molasses Extractmentioning

confidence: 99%

Evaluation of phenolic constituent, antioxidant and antibacterial activities of sugarcane molasses towards foodborne pathogens

Shafiqa-Atikah¹,

M.A.R.²,

Mahyudin³

et al. 2020

Food Res.

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The employment of chemical synthetic as an antimicrobial agent in inhibiting microbial growth has become a major concern due to adverse health impact, food safety crisis and the pressure on food manufacturers. Essential bioactive compound in sugarcane molasses, a by-product from a sugar refinery process could be effective as an alternative antimicrobial substance. However, their antimicrobial properties are not understandable. This study aimed 1) to detect the total phenolic compounds present in sugarcane molasses extract and 2) to determine the antioxidants and antibacterial activities of sugarcane molasses extract towards foodborne pathogens. The phenolic compounds of sugarcane molasses extract were determined by UHPLC-MSMS. Antioxidant activities were estimated by a total phenolic compound assay and a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Meanwhile, antibacterial activities were carried out via disc diffusion, minimum inhibition concentrations (MICs) and minimum bactericidal concentrations (MBCs) assays. In this study, several extracted compounds were identified in sugarcane molasses extract and included gallic acid, phenylvaleric acids, quinic acid, tannic acid and 6-C-glucosyl-8-C-arabinosyl apigenin or arabinoysl-glucosylapigenin. The sugarcane molasses extract showed high total phenolic compounds with values of 7.6 mg GAE/g extract. Meanwhile, antioxidant activities of sugarcane molasses extract were also found high and the 50% inhibitory concentration (IC 50 value) was about 0.79 mg QE/g. The inhibition zone against four foodborne pathogens, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli and Salmonella enterica serovar Typhimurium ranged from 8.82±0.3 mm to 25.05±1.6 mm. Meanwhile, the MICs of sugarcane molasses extract ranged from 3.125% to 6.25% v/v and MBCs were 6.25% to >12.5% v/v. In conclusion, sugarcane molasses extract is rich in phenolic compounds and has the potential to be applied as the natural antioxidant and antibacterial compounds.

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Total Phenolic Content and Antioxidant and Antibacterial Activities of Pereskia bleo

Cited by 84 publications

References 10 publications

Streptomyces sp. Strain MUSC 125 from Mangrove Soil in Malaysia with Anti-MRSA, Anti-Biofilm and Antioxidant Activities

Streptomyces sp. Strain MUSC 125 from Mangrove Soil in Malaysia with Anti-MRSA, Anti-Biofilm and Antioxidant Activities

Multi-step reflux extraction of bio-pharmaceutical phenolic bioactives from balsam apple (Momordica balsamina L.)

Evaluation of phenolic constituent, antioxidant and antibacterial activities of sugarcane molasses towards foodborne pathogens

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