Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort

Byberg, Liisa; Melhus, Håkan; Gedeborg, Rolf; Sundström, Johan; Ahlbom, Anders; Zethelius, Björn; Berglund, Lars; Wolk, Alicja; Michaëlsson, Karl

doi:10.1136/bmj.b688

Cited by 263 publications

(263 citation statements)

References 52 publications

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“…Given the importance of taking into account changes in physical activity over time, 14,15 we used data on physical activity from phases 5 and 7 (N =7456) to constitute 3 participant groups. For the biggest group, composed of those who responded at both phases (n = 5549), data on physical activity at phase 5 were used for their contribution to the calculation of person-years until phase 7, and then data at phase 7 were used until either death or the end of follow-up on April 30, 2009.…”

Section: Discussionmentioning

confidence: 99%

“…1,15,20,21 Few studies have investigated the independent effects of the various levels of physical activity. 1,6 One study found moderately vigorous (MET ‡ 4.5) but not lower energetic activities to be associated with reduced risk of mortality 22 ; others compared vigorous and nonvigorous activities and showed that only vigorous activities were associated with reduced risk of mortality.…”

Section: Comparison With Previous Studiesmentioning

confidence: 99%

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Effect of Intensity and Type of Physical Activity on Mortality: Results From the Whitehall II Cohort Study

et al. 2012

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Objectives. We examined the association of intensity and type of physical activity with mortality. Methods. We assessed the duration of physical activity by intensity level and type in 7456 men and women from the Whitehall II Study by questionnaire in 1997–1999 (mean ±SD age = 55.9 ±6.0 years) and 5 years later. All-cause mortality was assessed until April 2009. Results. A total of 317 participants died during the mean follow-up of 9.6 years (SD = 2.7). Reporting at least 1 hour per week of moderate activity was associated with a 33% (95% confidence interval [CI] = 14%, 45%) lower risk of mortality compared with less than 1 hour. For all physical activity types examined, except housework, a duration of physical activity greater than 0 (≥ 3.5 hours for walking) was associated with lower mortality in age-adjusted analyses, but only the associations with sports (hazard ratio [HR] = 0.71; 95% CI = 0.56, 0.91) and do-it-yourself activity (HR = 0.68; 95% CI = 0.53, 0.98) remained in fully adjusted analyses. Conclusions. It is important to consider both intensity and type of physical activity when examining associations with mortality.

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Section: Discussionmentioning

confidence: 99%

Section: Comparison With Previous Studiesmentioning

confidence: 99%

Effect of Intensity and Type of Physical Activity on Mortality: Results From the Whitehall II Cohort Study

et al. 2012

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“…Physical activity and good nutrition contribute to healthy ageing and reduces morbidity and mortality (79) . Physical activity has been shown to have protective effects against mortality in patients with chronic diseases such as CVD (80) .…”

Section: Physical Activity and Nutrition-based Interventionsmentioning

confidence: 99%

Locomotion, cognition and influences of nutrition in ageing

Ayers

2013

Proc. Nutr. Soc.

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Gait and cognitive impairments in older adults can reflect the simultaneous existence of two syndromes that affect certain brain substrates and pathologies. Nutritional deficiencies, which are extremely common among elderly population worldwide, have potential to impact the existence and rehabilitation of both syndromes. Gait and cognition are controlled by brain circuits which are vulnerable to multiple age-related pathologies such as vascular diseases, inflammation and dementias that may be caused or accentuated by poor nutrition or deficiencies that lead to cognitive, gait or combined cognitive and gait impairments. The following review aims to link gait and cognitive classifications and provide an overview of the potential impact of nutritional deficiencies on both neurological and gait dysfunctions. The identification of common modifiable risk factors, such as poor nutrition, may serve as an important preventative strategy to reduce cognitive and mobility impairments and moderate the growing burden of dementia and disability worldwide.

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“…The time horizon was set at five years to allow stabilization of the beneficial effects from exercise or medical therapy. 10,11 Main outcomes used for comparison between strategies were death, MI, and complications from coronary angiography.…”

Section: The Decision Modelmentioning

confidence: 99%

Is an Exercise Tolerance Test Indicated Before Beginning Regular Exercise? A Decision Analysis

2009

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Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort

Abstract: Objective To examine how change in level of physical activity after middle age influences mortality and to compare it with the effect of smoking cessation.

Cited by 263 publications

References 52 publications

Effect of Intensity and Type of Physical Activity on Mortality: Results From the Whitehall II Cohort Study

Effect of Intensity and Type of Physical Activity on Mortality: Results From the Whitehall II Cohort Study

Locomotion, cognition and influences of nutrition in ageing

Is an Exercise Tolerance Test Indicated Before Beginning Regular Exercise? A Decision Analysis

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