Torque teno sus virus (TTSuV) infection at different stages of pig production cycle

Leme, Raquel Arruda; Alfieri, Alice Fernandes

doi:10.1590/s0100-736x2013000700002

Cited by 7 publications

(3 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Coinfections of multiple genetically diverse anelloviruses have been reported in in humans (Okamoto et al, 1999) and also other mammals several studies (Biagini et al, 2007;Fahsbender et al, 2017;Huang et al, 2010;Kraberger et al, 2020b;Leme et al, 2013;Nishiyama et al, 2014). This was also evident for the feline TTFVs where blood samples from 17 individuals harboured between two and four distinct anellovirus species (Table 1).…”

Section: Co-infection Dynamicsmentioning

confidence: 59%

Complex evolutionary history of felid anelloviruses

et al. 2021

View full text Add to dashboard Cite

Section: Co-infection Dynamicsmentioning

confidence: 59%

Complex evolutionary history of felid anelloviruses

et al. 2021

View full text Add to dashboard Cite

“…The fecal–oral route is assumed to be the main route of infection for anelloviruses, but they are also transmitted by vertical and transplacental/intra-uterine route [ 33 , 34 ]. A Brazilian study showed similar results, suggesting that TTSuV detected in fecal samples spread to pigs of all production stages and that the viral infection rate increased with the age of the animals [ 35 ]. Similar to Blois et al [ 15 ], we could not find a difference between males and females concerning TTSuV1 prevalence.…”

Section: Discussionmentioning

confidence: 84%

First Report of TTSuV1 in Domestic Swiss Pigs

Polster

Lechmann

Lienhard

et al. 2022

Viruses

View full text Add to dashboard Cite

Serum prevalence of Torque teno sus viruses (TTSuV1 and k2; family Anelloviridae) is known to be high in the porcine population worldwide but pathogenesis and associated pathomorphological lesions remain to be elucidated. In this study, quantitative real-time PCR for detection of TTSuV1 was performed in 101 porcine samples of brain tissue, with animals showing inflammatory lesions or no histological changes. Additionally, a pathomorphological and immunohistochemical characterization of possible lesions was carried out. Selected cases were screened by TTSuV1 in situ hybridization. Furthermore, TTSuV1 quantitative real-time PCR in splenic and pulmonary tissue and in situ hybridization (ISH) in spleen, lungs, mesenteric lymph node, heart, kidney, and liver were performed in 22 animals. TTSuV1 was detected by PCR not only in spleen and lung but also in brain tissue (71.3%); however, in general, spleen and lung tissue displayed lower Ct values than the brain. Positive TTSuV1 results were frequently associated with the morphological diagnosis of non-suppurative encephalitis. Single TTSuV1-positive lymphocytes were detected by ISH in the brain but also in lungs, spleen, mesenteric lymph node and in two cases of non-suppurative myocarditis. A pathogenetic role of a TTSuV1 infection as a co-factor for non-suppurative encephalitides cannot be ruled out.

show abstract

“…On the other hand, TV-A, SV-A, and EV-G RNA detection in solid fecal samples could indicate that porcine enteric picornaviruses were not always associated with the occurrence of diarrhea in this study. To properly assess the association of the virus's presence with the occurrence of diarrhea, it is necessary to design a specific investigation, including the evaluation of infections with other porcine enteric viruses, such as rotaviruses, caliciviruses, picobirnavirus, Aichivirus C, Senecavirus A, and Torque teno sus virus, which are endemic in Brazilian pig herds [24,[29][30][31][32][33][34][35][36][37][38].…”

Section: Responsible Editor: Fernando Spilkimentioning

confidence: 99%