TORCH Screening Test in Pregnant Women of Kirkuk City

Obaid, Hiro M.; Juma, Shawbow A.

doi:10.23851/mjs.v27i5.162

Cited by 6 publications

(10 citation statements)

References 10 publications

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“…In this study approximately 1.4% of abortion samples are due to Herpes Simplex Virus which identified by PCR-technique, which is similar to study done in Al-Batool Teaching Hospital for Maternity and Children in Baqubah city, in which there were 2% incidence of HSV type1 and 2 in pregnant women (Hussein et al, 2017). On other hand these results are comparable with a study done in Azadi Teaching Hospital, Kirkuk, Iraq, in which incidence of HHSV by ELISA test was 2.6% (Obaid and Juma, 2017).…”

Section: Discussionsupporting

confidence: 89%

Frequency of Cytomegalovirus, Rubella, and Herpes Simplex Virus in Embryonic Tissues of Women With Missed Abortion

Ahmad¹,

Kareem²

2020

MJN

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Background and objectives: Spontaneous abortion (SA), also known as miscarriage, is considered as one of the most frequent problems a woman may face during early pregnancy, is not only related to morbidity or mortality, but also has an obvious social and psychological impact on women. An abortion is the removal or expulsion of an embryo or fetus from the uterus, resulting in \or caused by its death, the loss of a pregnancy occurs within the first 20-24 weeks of gestation, after which, fetal death is known as a stillbirth. This study was first aimed to assess the frequency of, Cytomegalovirus, Rubella and Herpes simplex virus in embryonic tissues of women with abortion. Next to find out the sociodemographic characteristics of the studied populations. Methods: This cross-sectional prospective study was carried out from February 2019 through January 2020.This study prospectively deal with tissues from conceptus after abortion which collected from maternity teaching hospital in Erbil city, Iraq for the diagnosis of frequency of CMV, rubella and herpes simplex virus. RT-PCR were used in tissue analysis. SPSS version 25 was used for data entry and analysis. Results: Out of 72 cases with spontaneous abortion 8 (11.1%) were due to human Cytomegalovirus,2 (2.8%) were due to Rubella virus and 1case (1.4%) was due to Herpes simplex virus, the age range of participants was 17-45 years with mean ± Sd of (31.29 ± 6.11) years. The highest percentages of participants were in their second and third decades of life (40.5% and 37.5% respectively) and about 86.1% of them were unemployed (housewives) and majority about 57% of them attending primary school, and more than half percentage (63.8%) of them have intermediate economic state. Histopathological analysis shows that out of 72 cases only 9 samples (16.6%) show histopathological abnormalities. A statistically significant association was found between Rubella infection and histopathological abnormality. Conclusions: Cytomegalovirus infection was more prevalent among the study samples, followed by Rubella infection then Herpes simplex virus infection by real-time polymerase chain reaction, on other hand 16.6% of samples shown nonspecific histopathological abnormality.

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Section: Discussionsupporting

confidence: 89%

Frequency of Cytomegalovirus, Rubella, and Herpes Simplex Virus in Embryonic Tissues of Women With Missed Abortion

Ahmad¹,

Kareem²

2020

MJN

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“…Toxoplsmosis is a disease of all regions and communities, the infection rate of the disease among pregnant women in this study was 9.8%, this was agreed with what found (8.9, 9.5%) by others (Obaid and Juma, 2016) but not agreed with higher rats (54%, 28.5) found by Tawfeeq et al, (2012) and Amin et al, (2013). The infection is endemic more in populations that unaware of prophylaxes and preventative strategies.…”

Section: Resultssupporting

confidence: 83%

“…The tissue cyst can transmit through ingestion of under cooked meat of infected animal (Dumetre and Darde, 2003).Toxoplasmosis is prevalent in our province (Kirkuk), the disease seroprevalence was 18.7% in healthy persons (Obaid et al, 2017). And 21.5% among university students (Obaid, 2017),36.53 % in married and unmarried women (Obaid, 2014), 15.5% in pregnant women (Obaid and Juma, 2016). In Muthana a prevalence of 44.5 % was recorded among pregnant women (ALseadawy, 2010).The anti-Toxoplasma gondii IgM and IgG rates were 22.2, 32.4% in Wassit pregnant women.…”

Section: Issn: 2319-7706 Volume 8 Number 02 (2019)mentioning

confidence: 98%

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Toxoplasma Sero-Prevalence and Related Knowledge Survey in Pregnant Women and University Staff

Obaid¹

2019

Int.J.Curr.Microbiol.App.Sci

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“…TORCH infections are associated with adverse foetal outcomes like recurrent abortions, IUFD, still birth, IUGR, congenital malformations and other reproductive failures especially during the first trimester of the pregnancy as placental transmission of IgG antibodies against these microorganisms from mother to foetus is more during first trimester and foetal immune system is unable to resist these microorganisms [39][40][41][42][43][44].…”

Section: Discussionmentioning

confidence: 99%

Study to Evaluate Association of Torch Infection with Bad Obstetric History in Pregnant Women at Sms Medical College and Attached Group of Hospitals, Jaipur

Panwar

Bithu

Yadav

et al. 2021

AJMAH

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Background: Congenital infections are transmissible in utero and it can lead to serious foetal outcomes. These infections can be early detected in pregnant women with bad obstetric history for better foetal outcomes. Aim of the Study was to evaluate the association of TORCH infection with bad obstetric history among pregnant women. Study Design: Observational and comparative study Place and Duration of Study: Central laboratory, Department of Microbiology, SMS Medical College, Jaipur between April 2020 and September 2021. Methodology: 260 blood samples of pregnant women (130 with bad obstetric history and 130 pregnant women without bad obstetric history) were collected. and tested for the presence of IgM and IgG antibodies against Toxoplasma gondii, Rubella virus, Cytomegalovirus by Chemiluminescence and Herpes simplex virus using ELISA kits. Results: Overall TORCH IgM seropositivity in high-risk pregnant women was 17.19%. In pregnant women with bad obstetric history, IgM Seropositivity for Toxoplasma gondii was 3.84% (P value .02), rubella 2.34% (P value .30), Cytomegalovirus 5.47% (P value .08), and 6.25% (P value .56) for Herpes-1 and 2 infections and IgG seropositivity for toxoplasma, rubella, cytomegalovirus and herpes virus was 16.41% (P value .001), 93.75% (P value .11), 98.44% (P value .55), 48.44% (P value .53) respectively. In pregnant women without bad obstetric history, IgM and IgG seropositivity for toxoplasma, rubella, cytomegalovirus and herpes virus was 0/0.77%, 0.76/97.69%, 1.53/99.23% and 4.61/44.62% respectively. The average age of the study population was 27.13 years. Conclusion: As TORCH infections are transmissible in-utero in all the stages of pregnancy and contributes in neonatal and infant deaths, so early diagnosis and appropriate interventions necessary which help in proper management of the pregnant women.

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TORCH Screening Test in Pregnant Women of Kirkuk City

Cited by 6 publications

References 10 publications

Frequency of Cytomegalovirus, Rubella, and Herpes Simplex Virus in Embryonic Tissues of Women With Missed Abortion

Frequency of Cytomegalovirus, Rubella, and Herpes Simplex Virus in Embryonic Tissues of Women With Missed Abortion

Toxoplasma Sero-Prevalence and Related Knowledge Survey in Pregnant Women and University Staff

Study to Evaluate Association of Torch Infection with Bad Obstetric History in Pregnant Women at Sms Medical College and Attached Group of Hospitals, Jaipur

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