We show that the dynamics of generic isolated quantum systems admits a topological classification which captures universal features of many-body wavefunctions far from equilibrium. Specifically, we consider two short-ranged entangled wavefunctions to be topologically equivalent if they can be interconverted via finite-time unitary evolution governed by a symmetry-respecting Hamiltonian. By analogy to the classification of symmetry-protected topological phases, we consider the projective action of the symmetry group on a time-evolved wavefunction to explicitly calculate this nonequilibrium topological classification, focussing on systems of strongly interacting bosons in a variety of symmetry classes. The physical consequences of the non-equilibrium classification are described. In particular, we show that the characteristic zero-frequency spectroscopic peaks associated with topologically protected edge modes will be broadened by external noise only when the system is trivial in the non-equilibrium classification. arXiv:1908.06875v1 [cond-mat.str-el]