“…Besides causing severe deterioration of visual quality, such complications are difficult to treat, and success is often limited. [12][13][14][15][16][17][18] Although several studies on decentration-induced aberrations after conventional 1,2,7 and wavefront-guided LRS 3,4,8,19 have been published, all assumed a perfect ablation and did not consider the inherent induction of HOA which occurs in real corneas as a result of wound healing and biomechanical effects. 20,21 The present study was conducted to investigate the effects of decentration of the laser ablation relative to the entrance pupil of the eye on LOA, HOA, and optical quality, in a cat photorefractive keratectomy (PRK) model.…”