Topographical variation of macular choroidal thickness with myopia

Abstract

ABSTRACT.Purpose: To study the association between topographical variation of choroidal thickness and myopic features in healthy eyes, using spectral domain optical coherence tomography (OCT). Methods: Choroidal thickness was measured at the foveal centre (CTF) and 1.5 mm superiorly (CTS), inferiorly (CTI), nasally (CTN) and temporally (CTT) from the foveal centre, using enhanced depth imaging OCT. The temporal width of b zone of peripapillary atrophy (bPPA) was measured on infrared fundus images. The ratio of bPPA width to vertical disc diameter (PVDR) was calculated to correct retinal magnification. Results: This study includes 85 eyes from 85 subjects who had a mean age of 53.9 AE 12.9 years, a mean axial length of 23.56 AE 0.82 mm, a mean refractive error of À0.14 AE 1.80 D, a mean bPPA width of 218.6 AE 181.3 lm and a mean PVDR of 0.13 AE 0.11. The CTF was thickest (266.4 AE 81.6), followed by CTS (256.2 AE 82.5 lm), CTT (251.7 AE 68.4 lm), CTI (247.7 AE 90.3 lm) and CTN (211.0 AE 76.5 lm). There were 31 eyes (36.5%) with CTT thicker than CTF. The CTT/CTF negatively correlated with refractive error (p = 0.012) and positively correlated with axial length (p = 0.031), bPPA width (p = 0.003) and PVDR (p = 0.006). Conclusions: There was a correlation between a thickened choroid, temporal to the foveal centre, with the severity of myopic components in normal eyes. Topographical changes might be induced by stretching of the choroid and sclera towards a temporal direction with eyeball elongation.

Juxtapapillary choroid is thinner in normal‐tension glaucoma than in healthy eyes

“…Third, eyes with gamma-zone PPA, which is known to be associated with an elongated eyeball (Dai et al 2013;Kim et al 2013b), were excluded from the present study. Such eyes may have different choroidal thickness characteristics (Cheong & Tan 2015;Lee et al 2015). Longer axial length has been consistently demonstrated to be associated with the thinner peripapillary choroidal thickness in previous studies (Maul et al 2011;Park et al 2014).…”

“…First, it may be due to the inclusion of different patient populations. Such eyes may have different choroidal thickness characteristics (Cheong & Tan 2015;Lee et al 2015). high tension + patients with NTG).…”

The choroid and lamina cribrosa is affected in patients with Parkinson's disease: enhanced depth imaging optical coherence tomography study

“…In the study of Lee et al., they investigated topographical variation of macular choroidal thickness with myopia (Lee et al. ). The inclusion criteria covered patients with −6 to +6 dioptres of spherical equivalent and the mean age was 53.9 ± 12.9 years.…”

“…We did not find significant difference or relation between refraction and LC or choroidal thickness in PD and control group. In the study of Lee et al, they investigated topographical variation of macular choroidal thickness with myopia (Lee et al 2015). The inclusion criteria covered patients with À6 to +6 dioptres of spherical equivalent and the mean age was 53.9 AE 12.9 years.…”

Changes in choroidal thickness after vitrectomy for epiretinal membrane combined with vitreomacular traction

“…; Lee et al. ). Alterations can be observed after treatments such as anti‐VEGF treatment for neovascular AMD and PCV, photodynamic therapy for CSCR and panretinal photocoagulation for proliferative diabetic retinopathy, and this may help in the estimation of treatment response (Kim et al.…”