Topical problems of chronic gastritis

Abstract

The authors propose the definition of chronic gastritis with a brief overview of the history of investigation of this diseases and its prevalence with special reference to (1) the bacterial profile and its role in the development of infectious and inflammatory process in gastric mucosa, (2) the modern state of and new trends in the classification of chronic gastritis including their advantages and disadvantages, (3) the relationship between chronic gastritis and functional gastroduodenal dyspepsia syndrome. It is concluded that mucous microflora plays an important factor in the development ofpathology but H.pylori is not its predominant component. Modern classifications of chronic gastritis provide a basis for a deeper insight into evolution of chronic gastritis and its transformation into cancer. The diagnosis of ‘chronic gastritis with functional gastroduodenal dyspepsia syndrome‘ is invalid.

History of chronic gastritis: How our perceptions have changed

“…At the beginning of the 20 th century independently of each other two scientists Faber and Konjetzny made a serious attempt to prove the presence of a morphologic substrate in CG[ 18 ]. Faber by introducing 10% formalin solution into the abdominal cavity protected GM from postmortem autolysis and putrefaction.…”

Histological features of chronic gastrointestinal pathology depending on the form of the disease

“…Chronic gastroduodenitis (CGD) is the most common form of chronic gastroduodenal disease in childhood, accounting 58-74% of gastric and duodenum diseases. CGDa chronic recurrent inflammatory disease, which is accompanied by non-specific structural adjustment of mucosa membrane (MM) and gastric and duodenal glandular apparatus (dystrophic, inflammatory and dysregenerating changes), disorder of secretory and motor function of the stomach and duodenal gland [1,2].…”