Topical negative pressure in managing severe peritonitis: A positive contribution?

Abstract

AIM:To assess the use of topical negative pressure (TNP) in the management of severe peritonitis. METHODS:This is a four-year prospective analysis from

Systematic review and evidence based recommendations for the use of Negative Pressure Wound Therapy in the open abdomen

“…Table 7; Grade D. The principle goal for application of NPWT in grade 4 OA, now that fascial closure is no longer possible, is to promote granulation tissue formation to create a suitable surface for rapid grafting ( Table 5). The degree of graft-take depends on the quality of the recipient wound bed, thus once granulation tissue has covered the surface of the exposed organs and a frozen abdominal wound is present, NPWT may be used to encourage rapid granulation tissue growth [68,69]. Under these circumstances the degree of adherence between the viscera and the abdominal wall is too far advanced to permit application of the non-adherent interface layer.…”

Caso Clínico: Manejo del Abdomen Abierto Séptico Mediante Sistema VAC

“…Perez et al, reportaron resultados similares usando terapia de presión negativa y el sistema de recambio por VAC en una serie de 37 pacientes que presentaron peritonitis severa y síndrome compartimental [13].…”

The Effect of Vacuum-Assisted Closure in Bacterial Clearance of the Infected Abdomen

“…Although VAC has proven its efficacy in improving survival in several studies [9,13], it is not clear how the negative pressure it creates contributes to the treatment of these patients. Many authors have implied a role of negative pressure in removing the microbial burden on the infected abdomen [8,12,13]. However, there is no evidence that VAC has such an effect.…”

“…Although evidence-based data are missing, topical negative pressure in patients with severe abdominal infection appears to make a positive contribution to the treatment of these critically ill patients [12,13]. An important issue to be addressed is whether negative abdominal pressure alters the composition of the bacterial population in the peritoneal cavity.…”