1995
DOI: 10.1016/0190-9622(95)90238-4
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Topical hydrogen peroxide treatment of ischemic ulcers in the guinea pig: Blood recruitment in multiple skin sites

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Cited by 58 publications
(59 citation statements)
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“…However the same study showed very minimal bactericidal effects of hydrogen peroxide. In another study carried out by Tur, hydrogen peroxide was found to significantly increase blood flow in ischemic ulcers in a model guinea pig (Tur et al, 1995). H 2 O 2 is widely used as an antiseptic to treat bedsores, broken blisters, animal bite wounds, sore throats, cuts and abrasions, and is readily available in pharmacies (3% concentration) (McGraw, 1984).…”
Section: Introductionmentioning
confidence: 96%
“…However the same study showed very minimal bactericidal effects of hydrogen peroxide. In another study carried out by Tur, hydrogen peroxide was found to significantly increase blood flow in ischemic ulcers in a model guinea pig (Tur et al, 1995). H 2 O 2 is widely used as an antiseptic to treat bedsores, broken blisters, animal bite wounds, sore throats, cuts and abrasions, and is readily available in pharmacies (3% concentration) (McGraw, 1984).…”
Section: Introductionmentioning
confidence: 96%
“…Several studies showed no positive or negative effects of H 2 0 2 on wound healing. [5][6][7][8] We started our study of the efficacy of H 2 0 2 3% in the management of PNS on two groups of our patients (B, D) and found that injection of H 2 0 2 3% into the sinus tract two minutes before the injection of the methylene blue gave better results regarding the recurrence rate and healing time in the closed as well as in the open methods. This is because H 2 0 2 causes an opening and, at the same time, lining of the tracts leading to precise delineation and prevents extra ordinary diffusion of methylene blue into normal tissue greatly minimizing the removal of unnecessary surrounding normal tissues and enhancing rapid healing and less rate of recurrence.…”
Section: Discussionmentioning
confidence: 99%
“…23 The therapeutic properties of honey in relation to wound healing have been comprehensively reviewed by Molan, 24-26 who catalogued the evidence for the ability of honey to promote rapid healing, reduce oedema, debride necrotic tissue, reduce in ammation, clear infection, stimulate tissue regeneration and counteract malodour. At a cellular level the mechanisms involved in promoting rapid healing are not yet well characterized, except that stimulation of angiogenesis 27 and broblast proliferation 28 by low concentrations of hydrogen peroxide have been described. Since manuka honey was used in this patient, generation of hydrogen peroxide is unlikely to have contributed to enhanced healing.…”
Section: Figurementioning
confidence: 99%