Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin

Abstract

Abstract. The effects of skin pores on skin topographic features can be reduced by decreasing excessive production and accumulation of sebum and elimination of comedones. Therefore, a cosmetic cleanser that regulates sebum homeostasis is required. In the present study, the effects of a cosmetic cleanser that contained Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis (DPC) was examined on the removal of sebum and on skin pore size. Healthy volunteers (n=23) aged 20-50 years were asked to apply the test materials to the face. Skin oil content, pore size, pore number and extracted sebum surface area were measured using various measurement methods. All the measurements were performed at pre-and post-application of the test materials. When the cosmetic cleanser containing DPC was applied to the skin, the oil content decreased by 77.3%, from 6.19 to 1.40. The number of skin pores decreased by 24.83%, from 125.39 to 94.23. Skin pore size decreased from 0.07 to 0.02 µm 3 (71.43% decrease). The amount of extracted sebum increased by 335% when the DPC cleanser was used. Compared to the control cleanser, skin oil content was significantly decreased when the cleanser that contained DPC was used. The cleanser containing DPC also decreased pore size and number. Finally, the DPC cleanser easily removed solidified sebum from the skin. IntroductionIn skin, the sebaceous glands produce and secrete sebum that consists of a complex mixture of lipids that include functions, such as photoprotection, antimicrobial activity, delivery of fat-soluble anti-oxidants to the skin surface and pro-and anti-inflammatory activity exerted by specific lipids for homeostasis (1,2). Excreted sebum also maintains the skin surface moisture via the formation of a lipid film on the skin (3). Sebum is excreted to the skin surface through the skin pore, which is an opening of the pilosebaceous unit (2). The skin pores affect the topographical features at the skin surface. Under specific conditions, enlarged funnel-shaped skin pores may be present. Skin pore widening is induced by various exogenous and endogenous factors, such as gender, genetic predisposition, aging, chronic ultraviolet light exposure, comedogenic xenobiotics, acne and seborrhea (4). Various factors induce excessive sebum synthesis and accumulation in the pilosebaceous unit, which also contributes to skin pore size (5). The enlarged skin pores can be visible as 'orange peel skin', which is a significant cosmetic problem (6). In addition, lipid oxidation solidifies accumulated sebum, which generates comedone formation (7).A cosmetic cleanser is required that reduces skin pore size by decreasing excessive sebum production and accumulation, and that eliminates comedones. The objective of the present study was to evaluate the effect of a cosmetic cleanser on the removal of sebum and on skin pore size. The cleanser contained a mixture of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis (DPC).Diospyros kaki folium (persimmon) is widely cul...

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The Invasive Species Reynoutria japonica Houtt. as a Promising Natural Agent for Cardiovascular and Digestive System Illness

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