Topical antifungal treatments for tinea cruris and tinea corporis

Fungal Infections From Human and Animal Contact

“…36 May have best success with distal subungual type and when upper nail surface is filed or is otherwise more easily penetrated. 6,38,39 Tavaborole 5% solution daily for 48 weeks (adults, toenails).…”

“…6,35 Treatment Common treatment regimens are summarized in Table 2. 6,8,15,16,27,[35][36][37][38][39][40][41] Localized superficial skin dermatophyte infections may be treated by topical antifungals. 6,8,36 Adding topical corticosteroids to topical antifungal treatment is not suggested by guidelines and does not alter the rate of mycological cure, but may improve time to clinical cure due to treatment of inflammation.…”

“…6,8,36 Adding topical corticosteroids to topical antifungal treatment is not suggested by guidelines and does not alter the rate of mycological cure, but may improve time to clinical cure due to treatment of inflammation. 36 Tinea capitis, tinea barbae and Majocchi's granuloma require oral antifungal therapy. 6,15,16,38 All treatments may require dosage and duration adjustments in immunocompromised individuals.…”

“…Use for 1-4 weeks. 6,8,36 Local reactions and irritations, pruritis, erythema, contact dermatitis, skin discoloration (may vary with product)…”

Perspective on animal models of dermatophytosis caused byTrichophyton rubrum

“…The clinical aspects of lesions are diversified and are a result of the delicate balance between the destruction of the keratin and the inflammatory response, which varies according to the etiologic agent and geographical localization. 5,6 Morphologically, T. rubrum may present hyaline hyphae, microconidia, and macroconidia in addition to chlamydoconidia and arthroconidia. 2,7 Moreover, all these components may be involved in the infection, and arthroconidia represent the main infective structure for humans.…”