Tophi as an initial manifestation of gout

Gupta, Akshita; Rai, Sharada; Sinha, Ruchi; Achar, Chandrayya

doi:10.4103/0970-9371.62192

Cited by 17 publications

(12 citation statements)

References 2 publications

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“…Tophaceous gout is characterized by macroscopic deposits of urate crystals found in periarticular and subcutaneous tissues, which predominantly are seen in the fingers, knee VOLUME 7 | NUMBER 6 | NOVEMBER/DECEMBER 2015 joints, volar aspect of the forearm, or helix of the ear (Gupta, Rai, Sinha, & Achar, 2009). Causes for elevated serum urate levels are decreased renal excretion, increased production of urate, and increased purine-rich foods (Chen & Schumacher, 2008).…”

Section: Pathophysiologymentioning

confidence: 97%

A Case Study of Tophaceous Gout

Sadighi¹

2015

Journal of the Dermatology Nurses' Association

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Tophaceous gout, presenting as nodules on the skin, is uncommon and can be mistaken for neoplasms. These nodules may not be recognized as gout because the clinical diagnosis of tophi gout is not always straightforward with typical symptoms. The cause for tophi gout is elevated serum uric levels, which result from decreased renal excretion, excessive production of urate, and a diet of purine-rich foods. Complications from tophi crystals may occur and can lead to secondary infections, decreased functionality of movement, and disfigurement. Patients need to be treated for acute attacks with complete resolution before long-term treatment is initiated to prevent an increase in the inflammatory cascade. Medications are effective in lowering urate levels and dissolving tophi, but the addition of dietary restrictions is also important to prevent reoccurrence of tophi crystals. Educating patients on early treatment of acute attacks and chronic treatment of high urate levels, along with dietary modification, lessens the possibility of complications that can occur from tophaceous gout.

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Section: Pathophysiologymentioning

confidence: 97%

A Case Study of Tophaceous Gout

Sadighi¹

2015

Journal of the Dermatology Nurses' Association

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“…These nodules may not be recognized as the clinical diagnosis of gout in many instances is not straightforward. In such setting fine needle aspiraton cytology of gouty tophi would facilitate the clinical diagnosis and treatment [5].…”

Section: Discussionmentioning

confidence: 99%

Cytodiagnosis of Gouty Arthritis

Mahore¹

2012

J Clin Case Rep

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“…[2], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21 ], [22], [23] Details of these are shown in ( …”

Section: Discussionmentioning

confidence: 99%

“…Bothale et al [13] 2012 1 Great toe Rheumatoid arthritis Koley et al [14] 2010 1 Bilateral feet and toes, left palm, right elbow, helix of left ear Arthritis Gupta et al [15] 2009 1 Left elbow joint and near the lateral malleolus of the left foot…”

Section: Not Givenmentioning

confidence: 99%

Cytodiagnosis of Gouty Tophi With Review of Literature

Singh

2017

IJCRR

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Fine needle aspiration cytology (FNAC) is a valuable diagnostic tool for the diagnosis of periarticular nodules. We present a case of forty five year old male with multiple soft tissue nodules on both the feet without any clinical and radiological features of arthritis. FNAC revealed needle shaped crystals consistent with monosodium urate crystals in amorphous granular debris. Diagnosis of gouty tophi was given. On follow up serum uric acid levels were found to be marginally high and a diagnosis of gout was established. FNAC is a valuable diagnostic tool for the diagnosis of periarticular nodules and pathologists should be aware of cytological features of gouty tophi.Keywords: FNAC, gouty tophi, monosodium urate crystals, uric acid Introduction:

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Tophi as an initial manifestation of gout

Cited by 17 publications

References 2 publications

A Case Study of Tophaceous Gout

A Case Study of Tophaceous Gout

Cytodiagnosis of Gouty Arthritis

Cytodiagnosis of Gouty Tophi With Review of Literature

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