Cytodiagnosis of Gouty Arthritis

Abstract

Gout is a disorder of uric acid metabolism that causes deposition of Monosodium Urate (MSU) crystals in joint spaces, which, in turn, elicit an acute inflammatory reaction. We present a case in which diagnosis of gout was made by fine needle aspiration of tophus. FNAC of gouty tophus is an easy alternative to synovial biopsy. It is simpler, easier and less painful.

Gouty Tophi of Small Joints of Hand: A Classical Presentation

“…Aspirate in gouty tophus is chalky white and on smears, there is a presence of slender needles-shaped crystals whereas the crystals in pseudogout are smaller, rhomboid in shape. The crystals in pseudogout are due to deposition of calcium pyrophosphate dihydrate (CPPD).Also, the gout crystals are negatively birefringent on polarized microscopy and CPPD crystals are weakly positive [4].…”

Cytodiagnosis of Gouty Tophi With Review of Literature

“…[2], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21 ], [22], [23] Details of these are shown in ( …”

“…Bothale et al [13] 2012 1 Great toe Rheumatoid arthritis Koley et al [14] 2010 1 Bilateral feet and toes, left palm, right elbow, helix of left ear Arthritis Gupta et al [15] 2009 1 Left elbow joint and near the lateral malleolus of the left foot…”

Gouty Tophi: FNAC Diagnosis and Review of Literature

“…The definitive diagnosis of gout is best established by demonstration of monosodium urate crystals . [1] The most common site is first metatarsophalangeal joint space. Fine needle aspiration cytology (FNAC) is simple, cost effective, safe procedure in diagnosing periarticular nodules.…”