Tobacco and the skin

Metelitsa, Andrei I.; Lauzon, Gilles J.

doi:10.1016/j.clindermatol.2010.03.021

Cited by 38 publications

(31 citation statements)

References 129 publications

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“…Occupational physicians can play an active role in smoking prevention and cessation and must provide their smoking employees incentive, guidance and intervention to help them discontinue this habit. Tobacco smoking is known to influence various inflammatory skin diseases [10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26]. An association between smoking and HE has been postulated [16,19,22,23,24,25,26] and the present findings underscore that smoking has a negative impact on work-related HE.…”

Section: Discussionsupporting

confidence: 57%

“…Thus, smoking has been shown to be a risk factor for developing lupus erythematodes [10,11,12], palmoplantar pustulosis [13,14,15] and, to some extent, also psoriasis [16,17]. Numerous studies have linked cigarette smoking with delayed wound healing and a number of wound-related complications [18]. Until now, contradictory findings have been reported concerning a possible association between tobacco smoking and HE [16,19,20,21,22,23,24,25,26].…”

Section: Introductionmentioning

confidence: 99%

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Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Kütting

Uter²,

Weistenhöfer³

et al. 2011

Dermatology

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Background: Although they know the long-term complications of smoking, many smokers require additional motivation for entering a smoking cessation programme. At the same time, smoking is considered a possible promoting factor for various skin diseases. Objective: The present study assesses the impact of smoking on occupational hand dermatitis in a high-risk population. Material and Methods: 1,355 metal workers, 97.3% of them shift workers, took part in a standardized interview and a dermatological examination of their hands. A subgroup of 1,020 males was willing to be followed-up for 1 year. Of those, 78.3% could be included in the final assessment. Results: Compared to the general German adult population the percentage of smokers was increased (41.7% at baseline). Probably due to self-selection bias and to a higher drop-out rate, the proportion of smokers was significantly lower at follow-up. Compared to nonsmokers, smokers had significantly higher score values for both erythematous lesions and vesicles. Conclusion: The present data might give additional support for occupational physicians or dermatologists to convince workers to quit smoking.

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Section: Discussionsupporting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Kütting

Uter²,

Weistenhöfer³

et al. 2011

Dermatology

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“…Given that smoking negatively affects a number cutaneous conditions, dermatologists are de facto active participants in smoking prevention and cessation, and must provide their smoker patients with incentive, guidance and intervention to help them discontinue the habit. 80 …”

Section: Resultsmentioning

confidence: 99%

Hydroxychloroquine and smoking in patients with cutaneous lupus erythematosus

Ezra

Jorizzo

2012

Clinical and Experimental Dermatology

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SummaryAntimalarials, such as chloroquine and hydroxychloroquine, have been used to treat cutaneous and systemic lupus erythematosus for decades with excellent therapeutic efficacy. Smoking seems to inhibit the therapeutic efficacy of antimalarials when treating cutaneous lupus erythematosus (CLE), but the reason behind this observation is unclear. In addition, antimalarials have been associated with several potentially serious adverse effects, including irreversible loss of vision. The aim of this literature review is to discuss the evidence for how cigarette smoking interferes with antimalarial efficacy in the treatment of CLE. Evidence-based data with long-term follow-up will allow determination of the aetiology for diminished antimalarial response, and enable selection of the best treatment to maximize long-term remission in CLE.

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“…Smoking not only induces inflammation, but also delays wound healing, partly because it decreases cutaneous blood flow and causes chronic damage to the microcirculation, thus compromising tissue oxygenation. In addition, fibroblast migration into lesional skin is inhibited (13,14). Smoking has been suspected to be a risk factor for skin diseases such as lupus erythematosus (15,16), palmoplantar pustulosis (17,18), psoriasis (19,20), and hidradentis suppurativa (21).…”

mentioning

confidence: 99%

Tobacco smoking and hand eczema – is there an association?

et al. 2015

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SummaryBackground. Numerous risk factors have been suggested for hand eczema. This systematic review evaluates the association between tobacco smoking and hand eczema. Objective. To review the literature systematically on the association between smoking and hand eczema. Methods. The PubMed and EMBASE databases were searched up to 27 January 2015 for articles on the association between tobacco smoking and hand eczema, including human studies in English and German only. Experimental studies, studies on tobacco allergy, case reports, reviews and studies on second-hand smoking were excluded. Results. Twenty articles were included. Among studies in occupational settings, three of seven found a statistically significant positive association between tobacco smoking and hand eczema prevalence rate, as did four of eight population-based studies. The association was stronger for studies in occupational settings than for population-based studies. No studies reported tobacco to be a clear protective factor for hand eczema. Two of five studies regarding severity found a positive association between smoking and hand eczema severity. Conclusion. Overall, the data indicate that smoking may cause an increased frequency of hand eczema, particularly in high-risk occupations. However, data from studies controlling for other risk factors are conflicting, and few prospective studies are available. Studies controlling for other risk factors are needed, and information regarding the diagnosis of subclasses of hand eczema, as well as severity, may be important.

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Tobacco and the skin

Cited by 38 publications

References 129 publications

Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Hydroxychloroquine and smoking in patients with cutaneous lupus erythematosus

Tobacco smoking and hand eczema – is there an association?

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