2017
DOI: 10.4103/jhrs.jhrs_105_16
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To study the vitamin D levels in infertile females and correlation of Vitamin D deficiency with AMH levels in comparison to fertile females

Abstract: Context:Human and animal data suggest that low vitamin D (25-hydroxyvitamin D) status is associated with impaired fertility, endometriosis, and polycystic ovary syndrome. Vitamin D regulates antimullerian hormone (AMH), FSH, mRNA, and expression of genes in reproductive tissues, implicating a role in female reproduction.Aims:To study the vitamin D levels in infertile females and to know the correlation of vitamin D deficiency (VDD) with serum AMH in infertile females compare to fertile females.Settings And Des… Show more

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Cited by 19 publications
(24 citation statements)
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“…Multivariate linear regression analysis of log-transformed AMH and FSH with 25OH-D levels adjusted for age, BMI, and seasonal variation confirmed a lack of association [57]. In a small case-control study by Lata et al [56], women with unexplained infertility were compared to fertile controls in terms of AMH and vitamin D levels. Vitamin D deficiency was present in 64.28% of infertile females.…”
Section: Observational Studiesmentioning
confidence: 85%
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“…Multivariate linear regression analysis of log-transformed AMH and FSH with 25OH-D levels adjusted for age, BMI, and seasonal variation confirmed a lack of association [57]. In a small case-control study by Lata et al [56], women with unexplained infertility were compared to fertile controls in terms of AMH and vitamin D levels. Vitamin D deficiency was present in 64.28% of infertile females.…”
Section: Observational Studiesmentioning
confidence: 85%
“…The current systematic review included eighteen cross-sectional studies and six interventional studies assessing the relationship between serum vitamin D levels and serum AMH levels. The cross-sectional studies demonstrated conflicting results, with several studies finding a positive correlation between serum AMH and vitamin D levels [42,46,50,61], while most studies reported largely negative findings [43][44][45]47,49,[51][52][53][54][55][56][57][58][59]. The systematic review and meta-analysis of the interventional studies revealed that vitamin D supplementations affect serum AMH levels but have opposite effects depending on the ovulatory statuses of the women.…”
Section: Discussionmentioning
confidence: 99%
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“…Vitamin D was also reported to enhance fertility on other aspects rather than PCOS, it was noted that it improves the success of in-vitro fertilization (12) , and protect against endometriosis (16)(17)(18)(19)(20) .While vitamin D impact on fertility and reproductive health is promising, data available are still inadequate and are not sufficient to establish a solid causal-effect relationship between fertility problems and vitamin D administration or deficiency. Further longitudinal multi-centric studies are still recommended to establish this hypothesis and to generate a consensus for usage of vitamin D in infertile patients.…”
Section: Dicussionmentioning
confidence: 99%
“…Furthermore, it has been involved in the pathogenesis of various female genital tract and reproductive disorders. [910]…”
Section: Introductionmentioning
confidence: 99%