To check or not to check? The application of meiotic studies to plant breeding

Martínez-Pérez, Enrique; Moore, Graham

doi:10.1016/j.pbi.2008.01.001

Cited by 35 publications

(26 citation statements)

References 45 publications

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“…This observation is in agreement with at least two studies in plants (Parker, 1975;Tease and Jones, 1975). It suggests that chromosomes that carry early recombination intermediates but ultimately fail to form a crossover may cause "the nucleus to linger in a recombination active state," in which a higher number of crossovers can be completed on the chromosomes that were correctly synapsed (Martinez-Perez and Moore, 2008). Thus, an important direction that studies should take is to analyze the effect of univalents on the frequency of meiotic recombination among the remaining chromosomes.…”

Section: Introductionsupporting

confidence: 91%

“…Likewise, Wang et al (2010) recently reported that in a rice (Oryza sativa) mutant for the central element protein ZEP1 of the synaptonemal complex, MER3, a component of the interfering crossover pathway, persisted for longer and crossover frequency increased. Therefore, these findings suggest that future studies should be directed toward investigating the control of meiotic progression (Martinez-Perez and Moore, 2008) as well as meiotic protein dynamics. This would especially be of interest in crop plants, where the appearance/disappearance of meiotic proteins could alter the recombination pattern across the genome.…”

Section: Discussionmentioning

confidence: 99%

“…Boosting crossovers would effectively speed up the combining of valuable traits from different parents in new elite varieties (Wijnker and de Jong, 2008), accelerate the removal of linkage drag during the introgression of valuable genes from exotic germplasms (Able and Langridge, 2006;Martinez-Perez and Moore, 2008), and facilitate the construction of highly recombinogenic lines and thus help improve genetic maps and positional cloning techniques. Recently, Carlton et al (2006) showed that the presence of a single pair of univalents during meiosis of Caenorhabditis elegans induces a compensatory increase in crossovers on the recombining chromosomes involved in bivalents of the same nuclei.…”

Section: Introductionmentioning

confidence: 99%

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Crossovers Get a Boost inBrassicaAllotriploid and Allotetraploid Hybrids

et al. 2010

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Meiotic crossovers are necessary to generate balanced gametes and to increase genetic diversity. Even if crossover number is usually constrained, recent results suggest that manipulating karyotype composition could be a new way to increase crossover frequency in plants. In this study, we explored this hypothesis by analyzing the extent of crossover variation in a set of related diploid AA, allotriploid AAC, and allotetraploid AACC Brassica hybrids. We first used cytogenetic methods to describe the meiotic behavior of the different hybrids. We then combined a cytogenetic estimation of class I crossovers in the entire genome by immunolocalization of a key protein, MutL Homolog1, which forms distinct foci on meiotic chromosomes, with genetic analyses to specifically compare crossover rates between one pair of chromosomes in the different hybrids. Our results showed that the number of crossovers in the allotriploid AAC hybrid was higher than in the diploid AA hybrid. Accordingly, the allotetraploid AACC hybrid showed an intermediate behavior. We demonstrated that this increase was related to hybrid karyotype composition (diploid versus allotriploid versus allotetraploid) and that interference was maintained in the AAC hybrids. These results could provide another efficient way to manipulate recombination in traditional breeding and genetic studies.

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Section: Introductionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Crossovers Get a Boost inBrassicaAllotriploid and Allotetraploid Hybrids

et al. 2010

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“…Whereas alternative approaches exist for some targets (for example, by coupling resequencing technologies with collections of natural or induced mutant alleles), for most traits it remains a serious impediment. Some promise may lie in manipulating patterns of recombination by either genetic or environmental intervention 47 . Quite strikingly, our data also reveal that a complex layer of post-transcriptional regulation will need to be considered when attempting to link barley genes to functions.…”

Section: Research Articlementioning

confidence: 99%

A physical, genetic and functional sequence assembly of the barley genome

2012

Nature

1,292

880

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Barley (Hordeum vulgare L.) is among the world's earliest domesticated and most important crop plants. It is diploid with a large haploid genome of 5.1 gigabases (Gb). Here we present an integrated and ordered physical, genetic and functional sequence resource that describes the barley gene-space in a structured whole-genome context. We developed a physical map of 4.98 Gb, with more than 3.90 Gb anchored to a high-resolution genetic map. Projecting a deep whole-genome shotgun assembly, complementary DNA and deep RNA sequence data onto this framework supports 79,379 transcript clusters, including 26,159 'high-confidence' genes with homology support from other plant genomes. Abundant alternative splicing, premature termination codons and novel transcriptionally active regions suggest that post-transcriptional processing forms an important regulatory layer. Survey sequences from diverse accessions reveal a landscape of extensive single-nucleotide variation. Our data provide a platform for both genome-assisted research and enabling contemporary crop improvement

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“…The original Ph1 deletion was defined to span a region of 70 Mbp; however, recent studies have reduced the size of this locus to 2.5 Mbp (Gill et al 1993;Roberts et al 1999;Griffiths et al 2006). This refined locus was found to contain seven Cyclin dependent kinase-like (Cdk-like) genes and a segment of subtelomeric heterochromatin, with the Cdk-like genes shown to be closely related to Cdk2 of human and mouse (Griffiths et al 2006;Martinez-Perez and Moore 2008). In addition, it has been shown that the Cdk-like genes of the 5B locus suppress the expression of the 5A and 5D Cdk-like loci, which are expressed at higher than normal levels in the absence of Ph1 (Al-Kaff et al 2008).…”

Section: The Classical Geneticsmentioning

confidence: 99%

Understanding meiosis and the implications for crop improvement

Able

Crismani

Boden

2009

Functional Plant Biol.

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Abstract. Over the past 50 years, the understanding of meiosis has aged like a fine bottle of wine: the complexity is developing but the wine itself is still young. While emphasis in the plant kingdom has been placed on the model diploids Arabidopsis (Arabidopsis thaliana L.) and rice (Orzya sativa L.), our research has mainly focussed on the polyploid, bread wheat (Triticum aestivum L.). Bread wheat is an important food source for nearly two-thirds of the world's population. While creating new varieties can be achieved using existing or advanced breeding lines, we would also like to introduce beneficial traits from wild related species. However, expanding the use of non-adapted and wild germplasm in cereal breeding programs will depend on the ability to manipulate the cellular process of meiosis. Three important and tightly-regulated events that occur during early meiosis are chromosome pairing, synapsis and recombination. Which key genes control these events in meiosis (and how they do so) remains to be completely answered, particularly in crops such as wheat. Although the majority of published findings are from model organisms including yeast (Saccharomyces cerevisiae) and the nematode Caenorhabditis elegans, information from the plant kingdom has continued to grow in the past decade at a steady rate. It is with this new knowledge that we ask how meiosis will contribute to the future of cereal breeding. Indeed, how has it already shaped cereal breeding as we know it today?

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To check or not to check? The application of meiotic studies to plant breeding

Cited by 35 publications

References 45 publications

Crossovers Get a Boost inBrassicaAllotriploid and Allotetraploid Hybrids

Crossovers Get a Boost inBrassicaAllotriploid and Allotetraploid Hybrids

A physical, genetic and functional sequence assembly of the barley genome

Understanding meiosis and the implications for crop improvement

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