Titanium Coating with Hydroxyapatite and Chitosan Doped with Silver Nitrate

Abstract

Biomaterials are effective alternatives for tissue substitution, including the bone tissue, since they do not pose risks of transmission of diseases or immune rejection. Nowadays, there is an interest in new materials capable of being associated with other substances which favor bone formation, especially natural biopolymers, in particular chitosan, which may present a potential for repairing bone defects and forms films that adhere to metal surfaces. Titanium, despite being a material greatly employed in implants because of its excellent physical properties, does not present bioactive characteristics, making it necessary to use methods of surface modification to enhance its biological response, favoring bone formation. This work aims at studying commercially pure titanium (cp-Ti) coating with chitosan using the biomimetic method and the evaluation of the effects of process variables as substrate surface conditions. Subsequently, the incorporation of AgNO3 was studied and its effects on corrosion resistance were evaluated. To evaluate the coating process, several tests were conducted, such as scanning electron microscopy, X-ray diffraction and infrared spectroscopy. From the results obtained, the efficacy of the chitosan film in inhibiting the corrosion of the metals is concluded, which was the target of this study, thus justifying its use for osseointegration and in several implants.

Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)

“…It was observed by Sousa (2018) that samples containing chitosan (Q) presented a similar behavior (Ti+HA+AgNO 3 +Q), but the rupture of the passive film occurred in superior potentials; thus, PCL will be more efficient than chitosan as medication releaser 32 .…”

A New Insight into Coating’s Formation Mechanism Between TiO2 and Alendronate on Titanium Dental Implant

“…One of strategies is to implant surface modification by inorganic coatings, like calcium phosphates (CaP) or hydroxyapatite (HA), that represent inorganic phase of the natural bone [ 1 , 2 , 4 , 7 , 8 , 9 , 10 , 11 , 12 ]. HA-based coatings on the titanium implants are responsible for osteoconductivity, bioactivity, and stability of the bone/implant connection.…”

Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing

“…This proves that not only the ionic constitution, but also the manufacturing method of the metal alloys, are directly related to the interaction of the implant with the recipient tissue. Other studies support this information because they find an absence of immunological reactions and, in the case of titanium, it is due to the dense and well-adhered oxide layer that is formed in contact with different environments, such as air or water [29,35,[69][70][71][72]. Other researchers claim that the stable and protective oxide layer helps to connect the extracellular matrix to the implant surface [73,74].…”