Tissue response to polypropylene meshes used in the repair of abdominal wall defects

Bellón, Juan M.; Contreras, Luis A.; Buján, Julia; Palomares, Daniel E.; Martín, Antonio Carrera-San

doi:10.1016/s0142-9612(97)00162-2

Cited by 80 publications

(64 citation statements)

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“…However, surgical meshes have brought with them several complications, such as fistulas and adhesions, especially with intraperitoneal use 2,7,14,[16][17][18][19] . Postoperative adhesions to the surgical meshes may bring complications such as bowel obstruction, female infertility, postoperative abdominal pain, and repair difficulties in future surgeries 25 .…”

Section: ■ Discussionmentioning

confidence: 99%

“…Hence, the use of surgical meshes for correction of abdominal hernias was strengthened due to its lower recurrence rates [6][7][8][9][10][11][12][13][14] . With the advent of laparoscopic surgery and the placement of intraperitoneal meshes, major adhesion formation was highlighted 2,7,[14][15][16][17][18][19] . The composite meshes -which have the surface facing the viscera made of absorbable and microporous material and the surface facing the muscles made of synthetic macroporous material -are the ones with the best results 20,21 .…”

Section: ■ Introductionmentioning

confidence: 99%

“…The search for the ideal composition became necessary with the introduction and development of laparoscopic repair of abdominal hernias, which required intraperitoneal mesh fixation 4,22 . Among the surgical meshes available on the market, the polypropylene ones are the most commonly used nowadays 4,16,18 . Polypropylene is a carbon-based materialwhich can be monofilament or multifilament -of easy handling, low cost, and non-biodegradable.…”

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confidence: 99%

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Comparative study of Polypropylene versus Parietex composite®, Vicryl® and Ultrapro® meshes, regarding the formation of intraperitoneal adhesions

et al. 2017

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Purpose: To compare the polypropylene mesh (Marlex®) to Vicryl®, Parietex composite® and Ultrapro® meshes to assess the occurrence of adhesions in the intraperitoneal implantation. Methods: Sixty Wistar rats were allocated into three groups: PP+V, in which all the animals received a polypropylene and a Vicryl® mesh; PP+PC, with the implantation of polypropylene and Parietex composite® meshes and PP+UP, in which there was implantation of polypropylene and Ultrapro®. Macroscopic analysis was performed 28 days later to assess the percentage of mesh area affected by adhesion. Results: in the PP+ V group, the Vicryl® mesh showed lower adhesion formation (p=0.013). In the PP+PC, there were no differences between polypropylene and Parietex composite® (p=0.765). In the PP+UP group, Ultrapro® and polypropylene meshes were equivalent (p=0.198). Conclusion: All the four meshes led to adhesions, with the Vicryl® mesh showing the least potential for its formation.

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Section: ■ Discussionmentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Comparative study of Polypropylene versus Parietex composite®, Vicryl® and Ultrapro® meshes, regarding the formation of intraperitoneal adhesions

et al. 2017

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“…The polypropylene implant has the characteristic of being monofilament, it tolerates well the presence of infection when compared to other synthetic meshes, since the small pores decrease the opportunity for bacterial growth (MILLIKAN, 2003). In addition, polypropylene mesh remains soft and flexible and it is not subject to weakening by the action of enzymes, providing a suitable frame for the deposition of collagen and embedding adjacent tissues (BELLON et al, 1998). However, according to Araújo et al (2010), the inflammatory process is more intense in animals that have received polypropylene implants when compared to the receptors that have attached biological biomaterials.…”

Section: Discussionmentioning

confidence: 99%

Hernioplasty with polypropylene implant after an abdominal trauma of a pregnant cat

Freitas

Filho

Silveira

et al. 2017

AVB

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“…Polypropylene meshes are amongst the most commonly employed biomaterials. It is well tolerated by the organism, it gets integrated to surrounding tissues and offers a great resistance degree to traction on the repair zone 1 . Furthermore, it is a resistant material, of easy manipulation and of low relactive cost, but it easily leads to adhesion formation that may result in postoperative abdominal pain, intestinal obstruction and fistulae formation 2,3 .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall

Paulo¹,

Malmonge

Menezes³

et al. 2010

Acta Cir. Bras.

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Purpose: To verify if the composit poli (2-hydroxyethyl methacrylate)-PolyHEMA/polypropylene mesh implanted in the female rat's abdominal wall could be suitable for the prevention of peritoneal adhesions, and for the evaluation of the tecidual response produced by this biomaterial. Methods: Polypropylene meshes (Group PP, n=20) and polypropylene meshes coated with a layer of poli (2-hydroxyethyl methacrylate)-PolyHEMA (Group PH, n=20) were implanted on the abdominal wall of Wistar female rats. Ten animals from each group were submitted to euthanasia at 15 and 30 days of the postoperative period. Results: The animals from the group PP presented visceral adhesions on the mesh surface, which was not observed in the ones from group PH. At the histopathological examination foreign body response was observed in both groups, whilst there was a greater intensity of inflammatory response in group PH on both moments. Conclusion: The poli (2-hydroxyethyl methacrylate) polyHEMA hydrogel associated to polypropylene mesh reduces visceral adhesion formation in rats, although it may be associated to greater inflammatory reaction. Key words: Peritoneum. Tissue Adhesions. Hydrogel. Polymers. Surgical Mesh. Polypropylenes. Biocompatible Materials. Rats. RESUMOObjetivo: Verificar se compósito poli 2-hidroxietil dimetacrilato (PoliHEMA) / tela de polipropileno implantado na parede abdominal de ratas seria adequado para prevenção de aderências peritoneais e avaliar a resposta tecidual desencadeada por este biomaterial. Métodos: Foram implantadas telas de polipropileno -Grupo PP (n=20) e telas de polipropileno revestidas por uma camada de poli 2 (hidroxietil dimetacrilato)-PolyHEMA -Grupo PH (n=20) na parede abdominal de ratas da linhagem Wistar. Dez animais de cada grupo foram submetidos à eutanásia aos 15 e 30 dias de pós-operatório. Resultados: Os animais do grupo PP apresentaram aderências viscerais na superfície da tela, o que não foi observado nos do grupo PH. Observou-se no exame histopatológico resposta tipo corpo estranho nos dois grupos sendo que no grupo PH houve maior intensidade de resposta inflamatória nos dois momentos. Conclusão: O hidrogel de poliHEMA quando associado à tela de polipropileno reduz a formação de aderências viscerais em ratos, embora possa estar associado à reação inflamatória mais intensa.

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Tissue response to polypropylene meshes used in the repair of abdominal wall defects

Cited by 80 publications

References 0 publications

Comparative study of Polypropylene versus Parietex composite®, Vicryl® and Ultrapro® meshes, regarding the formation of intraperitoneal adhesions

Comparative study of Polypropylene versus Parietex composite®, Vicryl® and Ultrapro® meshes, regarding the formation of intraperitoneal adhesions

Hernioplasty with polypropylene implant after an abdominal trauma of a pregnant cat

Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall

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