Tissue fibrinolytic activity in the anterior segment of the eye, as related to aqueous outflow

Saiduzzafar, H.

doi:10.1016/s0014-4835(70)80041-0

Cited by 6 publications

(2 citation statements)

References 6 publications

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“…As mentioned in the introduction, Pandolfi (1967) found that infusion of the fibrinolytic activator plasmin reduced the outflow resistance in eyes removed from apes. In agreement with this Saiduzzafar (1970) found that tranexamic acid injected into the anterior chamber of apes increased the outflow resistance. Both authors have found that there is a considerable fibrinolytic activity especially localised in and around Schlemm's canal.…”

Section: Discussionsupporting

confidence: 86%

A Double‐blind Study on the Influence of Tranexamic Acid on the Intraocular Pressure and the Central Corneal Thickness After Trabeculectomy for Glaucoma Simplex

Bramsen¹

1978

Acta Ophthalmologica

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The influence of tranexamic acid on the intraocular pressure and central corneal thickness has been examined by means of a double-blind trial in patients with glaucoma simplex. The material comprised 28 patients (14 pairs) who had all been operated on for glaucoma in one eye by trabeculectomy. Tranexamic acid was found not to influence the intraocular pressure, neither in the operated eye nor in the opposite eye. The possible antifibrinolytic effect on the outflow of the aqueous humour is discussed. As in previous studies an effect of tranexamic acid on the central corneal thickness was found in both the operated and in the non-operated eye. A possible mechanism behind this is discussed.

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Section: Discussionsupporting

confidence: 86%

A Double‐blind Study on the Influence of Tranexamic Acid on the Intraocular Pressure and the Central Corneal Thickness After Trabeculectomy for Glaucoma Simplex

Bramsen¹

1978

Acta Ophthalmologica

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“…The mechanism of facility increase is unknown, but it is possible that various PG's activate the plasminogen normally found in the anterior segment of the eye (6) and that the plasmin formed increases the facility of outflow (7). Iloprost (ZK36374), a stable PGI?…”

Section: Introductionmentioning

confidence: 99%

The Effect of Iloprost on the Rabbit Eye

Moses

Schmoll²,

Dihenia³

1986

Journal of Ocular Pharmacology and Therapeutics

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�ber den Einflu� von Corticosteroiden auf die fibrinolytische Aktivit�t verschiedener Gewebe des Auges

Arnold

1981

Albrecht von Graefes Arch. Klin. Ophthalmol.

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The influence of corticosteroids on the fibrinolytic activity in different tissues of the eye was investigated. Rats were treated with corticosteroids, and the fibrinplate method of Todd 1962) was used to estimate the fibrinolytic activity. After 14 days treatment with corticosteroids the fibrinolytic activity decreased. In the control eyes no fibrinolytic activity was left after 6 h of autolysis. The eyes treated with corticosteroids, however, still had fibrinolytic activity.

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Tissue fibrinolytic activity in the anterior segment of the eye, as related to aqueous outflow

Cited by 6 publications

References 6 publications

A Double‐blind Study on the Influence of Tranexamic Acid on the Intraocular Pressure and the Central Corneal Thickness After Trabeculectomy for Glaucoma Simplex

A Double‐blind Study on the Influence of Tranexamic Acid on the Intraocular Pressure and the Central Corneal Thickness After Trabeculectomy for Glaucoma Simplex

The Effect of Iloprost on the Rabbit Eye

�ber den Einflu� von Corticosteroiden auf die fibrinolytische Aktivit�t verschiedener Gewebe des Auges

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