Tissue engineering in dentistry

Earthman, James C.; Sheets, Cherilyn G.; Paquette, Jacinthe M.; Kaminishi, Ronald M.; Nordland, W. Peter; Keim, Robert G; Wu, Jean C.

doi:10.1016/s0094-1298(03)00080-4

Cited by 18 publications

(7 citation statements)

References 24 publications

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“…The concept of regenerative medicine is so broad that it can also involve products authorized as medical devices. For example, platelet-rich plasma is widely used in orthopedics, but also in dentistry or aesthetic medicine [ 6 , 7 ]. Separation kits for such plasma require standard notification as a medical device.…”

Section: Introductionmentioning

confidence: 99%

Collagen-Based Materials Modified by Phenolic Acids—A Review

Kaczmarek

Mazur

2020

Materials

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Collagen-based biomaterials constitute one of the most widely studied types of materials for biomedical applications. Low thermal and mechanical parameters are the main disadvantages of such structures. Moreover, they present low stability in the case of degradation by collagenase. To improve the properties of collagen-based materials, different types of cross-linkers have been researched. In recent years, phenolic acids have been studied as collagen modifiers. Mainly, tannic acid has been tested for collagen modification as it interacts with a polymeric chain by strong hydrogen bonds. When compared to pure collagen, such complexes show both antimicrobial activity and improved physicochemical properties. Less research reporting on other phenolic acids has been published. This review is a summary of the present knowledge about phenolic acids (e.g., tannic, ferulic, gallic, and caffeic acid) application as collagen cross-linkers. The studies concerning collagen-based materials with phenolic acids are summarized and discussed.

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Section: Introductionmentioning

confidence: 99%

Collagen-Based Materials Modified by Phenolic Acids—A Review

Kaczmarek

Mazur

2020

Materials

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“…[104][105][106] In addition, this strategy can serve as a delivery system for growth factors, adhesion molecules, and cytokines. 42,105,107,108 This approach has wide application in a variety of settings in dentistry. 106,109 In addition to replacing damaged or missing tissue or organs, the convergence of these fields will play an important role in developing a deeper understanding of tissue and organ regeneration and lead to innovative approaches to tissue and organ replacement.…”

Section: Tissue Engineering Stem Cell Biology Advanced Biomaterialsmentioning

confidence: 99%

Research and Discovery Science and the Future of Dental Education and Practice

Polverini¹,

Krebsbach

2017

Journal of Dental Education

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Dental graduates of 2040 will face new and complex challenges. If they are to meet these challenges, dental schools must develop a research and discovery mission that will equip graduates with the new knowledge required to function in a modern health care environment. The dental practitioner of 2040 will place greater emphasis on risk assessment, disease prevention, and health maintenance; and the emerging discipline of precision medicine and systems biology will revolutionize disease diagnosis and reveal new targeted therapies. The dental graduate of 2040 will be expected to function effectively in a collaborative, learning health care system and to understand the impact of health care policy on local, national, and global communities. Emerging scientific fields such as big data analytics, stem cell biology, tissue engineering, and advanced biomimetics will impact dental practice. Despite all the warning signs indicating how the changing scientific and heath care landscape will dramatically alter dental education and dental practice, dental schools have yet to reconsider their research and educational priorities and clinical practice objectives. Until dental schools and the practicing community come to grips with these challenges, this persistent attitude of complacency will likely be at the dental profession's peril. This article was written as part of the project "Advancing Dental Education in the 21 Century."

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“…Tissue-engineered odontogenesis One important goal of dental research is the efficient regeneration of lost teeth [1,2]. Tooth formation, or odontogenesis, is a complex process that has been characterized as a series of reciprocal epithelial-mesenchymal interactions, culminating in the differentiation of the interacting tissues [3][4][5][6].…”

Section: Chapter 5 Toothmentioning

confidence: 99%

Tooth

Ueda

2011

Applied Tissue Engineering

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Tissue engineering in dentistry

Cited by 18 publications

References 24 publications

Collagen-Based Materials Modified by Phenolic Acids—A Review

Collagen-Based Materials Modified by Phenolic Acids—A Review

Research and Discovery Science and the Future of Dental Education and Practice

Tooth

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