Tinnitus- related distress: evidence from fMRI of an emotional stroop task

Golm, Dennis; Schmidt‐Samoa, Carsten; Dechent, Peter; Kröner‐Herwig, Birgit

doi:10.1186/s12901-016-0029-1

Cited by 25 publications

(17 citation statements)

References 83 publications

(86 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Complementing the current findings, there is rich evidence showing exaggerated emotional Stroop interference at the behavioral level across a variety of patient populations (Bar-Haim et al, 2007;Cox et al, 2006;Epp et al, 2012;Field et al, 2009;Williams et al, 1996). Moreover, evidence from recent brain imaging studies has suggested a common neurobiological substrate across psychopathological disorders (Goodkind et al, 2015;McTeague et al, 2017;Sha et al, 2017;Sprooten et al, 2017). For instance, McTeague et al (2017) identified a common neural circuit (e.g., dlPFC) disruption across psychiatric diagnoses and cognitive control tasks that parallels the currently observed cognitive control network.…”

Section: Trans-diagnostic Pattern Of Hyper-activation and Clinical Sisupporting

confidence: 70%

“…This ALE map is assessed against a null-distribution of random spatial associations between studies using a non-linear histogram integration algorithm (Eickhoff et al, 2012;Turkeltaub et al, 2012). In addition, the average non-linear contribution of each experiment for each cluster was calculated from the fraction of the ALE values at the cluster with and without the respective experiment (Eickhoff et al, 2016). Based on the calculated contribution, we employed an additional two criteria to select significant clusters: (1) the contributions to one cluster were from at least two experiments to prevent the findings from being driven by the results from a single study; and (2) the average contribution of the most dominant experiment (MDE) did not exceed 50%, and the average contribution of the two most dominant experiments (2MDE) did not exceed 80% (Eickhoff et al, 2016).…”

Section: Main Activation Likelihood Estimation (Ale) Approachmentioning

confidence: 99%

See 1 more Smart Citation

Neural substrates of the emotion-word and emotional counting Stroop tasks in healthy and clinical populations: A meta-analysis of functional brain imaging studies

et al. 2018

View full text Add to dashboard Cite

The emotional Stroop task (EST) is among the most influential paradigms used to probe attention-related or cognitive control-related emotional processing in healthy subjects and clinical populations. The neuropsychological mechanism underlying the emotional Stroop effect has attracted extensive and long-lasting attention in both cognitive and clinical psychology and neuroscience; however, a precise characterization of the neural substrates underlying the EST in healthy and clinical populations remains elusive. Here, we implemented a coordinate-based meta-analysis covering functional imaging studies that employed the emotion-word or emotional counting Stroop paradigms to determine the underlying neural networks in healthy subjects and the trans-diagnostic alterations across clinical populations. Forty-six publications were identified that reported relevant contrasts (negative > neutral; positive > neutral) for healthy or clinical populations as well as for hyper- or hypo-activation of patients compared to controls. We demonstrate consistent involvement of the vlPFC and dmPFC in healthy subjects and consistent involvement of the vlPFC in patients. We further identify a trans-diagnostic pattern of hyper-activation in the prefrontal and parietal regions. These findings underscore the critical roles of cognitive control processes in the EST and implicate trans-diagnostic cognitive control deficits. Unlike the current models that emphasize the roles of the amygdala and rACC, our findings implicate novel mechanisms underlying the EST for both healthy and clinical populations.

show abstract

Section: Trans-diagnostic Pattern Of Hyper-activation and Clinical Sisupporting

confidence: 70%

Section: Main Activation Likelihood Estimation (Ale) Approachmentioning

confidence: 99%

Neural substrates of the emotion-word and emotional counting Stroop tasks in healthy and clinical populations: A meta-analysis of functional brain imaging studies

et al. 2018

View full text Add to dashboard Cite

show abstract

“…It may be possible that the severity and frequency of tinnitus‐related emotional states (distress and depression) in the two tinnitus groups are significantly different. New insights into the neurobiology of tinnitus suggest that neuronal changes occur not only on the classical auditory pathways but also on the insula, anterior cingulate cortex (ACC), amygdala, dorsolateral prefrontal cortex, orbitofrontal cortex, and (para) hippocampus (PHC; Golm, Schmidt‐Samoa, Dechent, & Kroner‐Herwig, ; Joos et al., ; Simonetti & Oiticica, ). These neuroanatomical changes play a specific role in both tinnitus‐related emotional state disorder and cognitive deficits (Araneda et al., ; Kraus & Canlon, ; Simonetti & Oiticica, ; Vanneste et al., ).…”

Section: Discussionmentioning

confidence: 99%

The characteristics of cognitive impairment in subjective chronic tinnitus

Wang

Zhang

et al. 2018

Brain and Behavior

View full text Add to dashboard Cite

IntroductionSubjective chronic tinnitus is a common medical syndrome with a high frequency of cognitive impairment; however, the characteristics of cognitive impairment in chronic tinnitus are poorly understood. Investigating the scope of cognitive impairment across the severity spectrum of tinnitus patients may shed light on the issue.MethodsA consecutive series of 207 subjective chronic tinnitus patients were classified into mild tinnitus group (n = 95) and severe tinnitus group (n = 112) by THI score (the cutoff THI scores were 37/38). These patients were assessed using the Cognitive Abilities Screening Instrument (CASI) and P300 event‐related potential.ResultsAlthough pure tone averages were not different between mild or severe tinnitus patients, severe tinnitus patients scored lower on the CASI assessment as well as almost all subdomains of CASI, particularly in items such as “short‐term memory,” “concentration or mental manipulation,” “orientation,” “abstraction and judgment,” “language abilities,” and “visual construction.” Furthermore, compared to mild tinnitus patients, severe tinnitus patients exhibited longer N2 and P3 latencies. Finally, a correlation analysis revealed that tinnitus severity was negatively correlated with CASI score and positively correlated with N2 and P3 latencies.ConclusionsThis study reveals that tinnitus patients on the severe end of the spectrum may be at risk for serious cognitive deficits, which may not be a secondary response to disease manifestations but a primary feature of the underlying disease.

show abstract

“…Brain activity of high- and low-distress tinnitus patients has also been investigated during fMRI cognitive/emotional tasks. Patients with high distress (compared to low-distress) tinnitus showed increased activation in the left mid frontal gyrus in response to tinnitus-related sounds versus neutral sentences [ 72 ], or in the right insula and orbitofrontal cortex in the tinnitus-related sounds versus neutral words contrast [ 73 ]. Decreased activation of the frontal areas in patients with more bothersome tinnitus, relative to those who do not suffer from it so much, was found when they listening to affective sounds not associated with tinnitus [ 74 ].…”

Section: Introductionmentioning

confidence: 99%

Electrophysiological correlates of focused attention on low- and high-distressed tinnitus

et al. 2020

View full text Add to dashboard Cite

Objectives The study aimed at determining the EEG correlates of concentration on either low or high-distressed tinnitus. Methods Sixty-seven patients (36 women, mean age = 50.34 ± 12.94 years) with chronic tinnitus were assigned to either a high (HD) or low (LD) tinnitus-related distress group based on THI results. All participants took part in the EEG study comprising two 3–4 min blocks of focusing on either tinnitus (Tinnitus Focus Condition, TFC) or the sensations from one’s own body (Body Focus Condition, BFC). The absolute power and current density of 8 frequency bands in 7 clusters were compared between conditions and groups. Results The most pronounced differences were found in the HD patients in the TFC, relative to the BFC, i.e. reduced power of frontally distributed low alpha (8–10 Hz) and posterior high alpha (10–12 Hz) as well as lower current density of 8–10 Hz rhythm over the right frontal/anterior cingulate cortex and higher middle beta (15–18 Hz) density in the precuneus. The HD, relative to LD patients, in both conditions, exhibited increased low beta (12–15 Hz) power over the left middle area and greater higher beta (15–25 Hz) power in the left posterior region. Conclusions The present study contrasted bioelectrical activity, acquired when concentrating on tinnitus with EEG data collected whilst patients focused on their body. Decreased alpha power and current density in the frontal/cingulate cortex when listening to bothersome tinnitus might reflect greater cortical arousal whereas increased beta power and density in the precuneus/posterior cingulate activity in this condition could be indicative for elevated tension or augmented cognitive/emotional processing of tinnitus sound. Enhanced beta rhythm in patients with high versus low tinnitus distress, observed independently of the study condition, may be due to greater self-focused attention or more active processing of sensations derived from the own body.

show abstract

Tinnitus- related distress: evidence from fMRI of an emotional stroop task

Cited by 25 publications

References 83 publications

Neural substrates of the emotion-word and emotional counting Stroop tasks in healthy and clinical populations: A meta-analysis of functional brain imaging studies

Neural substrates of the emotion-word and emotional counting Stroop tasks in healthy and clinical populations: A meta-analysis of functional brain imaging studies

The characteristics of cognitive impairment in subjective chronic tinnitus

Electrophysiological correlates of focused attention on low- and high-distressed tinnitus

Contact Info

Product

Resources

About