Objective
Investigate trends in incidence of lens extraction over the past twenty years.
Design
Longitudinal population-based cohort study.
Participants
Persons who participated in the Beaver Dam Eye Study.
Methods
Eligible persons 43–84 years of age living in the city or township of Beaver Dam, Wisconsin were recruited in 1987–1988. Participants were followed up every five years in 1993–1995, 1998–2000, 2003–2005, and 2008–2010 after the baseline examination in 1988–1990. Examinations consisted of ocular examination with lens photography and grading, medical history, measurements of blood pressure, height, and weight. Adjustments were made for age and sex. Values of risk variables were updated, and incidence of cataract surgery was calculated in each 5-year interval.
Main Outcome Measure
Incidence of lens extraction with regard to presence of clinically significant lens opacity and visual function.
Results
Age- and sex-adjusted incidence of lens extraction increased over the four 5-year intervals from 1.8% (95% confidence interval [CI] 1.3% to 2.5%) in the interval between the first and second study examinations to 11.7% (95% CI 9.9% to 13.8%) in the most recent study interval. The increase in incidence of surgery was significantly higher at successive intervals in persons without clinically significant lens opacity at each preceding examination (interval 1: 0.8% [95% CI 0.6% to 1.1%]; interval 4: 9.4% [7.8% to 11.2%]) compared with persons with at least one detectable type of opacity (interval 1: 9.2% [95% CI 6.4% to 13.2%]; interval 4: 16.5% [13.4% to 20.0%]). Recency of examination was not attenuated by adjusting for additional risk factors. There was no evidence that the increased incidence in surgery was preceded by poorer visual acuity, near vision, or contrast sensitivity at the beginning of each interval.
Conclusion
The incidence of lens extraction has increased over the past 20 years in persons older than the age of 65. The relative increase of surgery is higher in those without any clinically significant lens opacity, and in persons with visual acuity better than 20/40 at an exam as measured five years prior to observed incidence of lens extraction.