Time to resolution and effect on quality of life of molluscum contagiosum in children in the UK: a prospective community cohort study

Olsen, Jonathan; Gallacher, John; Finlay, A.Y.; Piguet, Vincent; Francis, Nick

doi:10.1016/s1473-3099(14)71053-9

Cited by 55 publications

(43 citation statements)

References 26 publications

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“…Topical application of KOH, imiquimod or another topical immunostimulatory agent is an alternative . Impact on the children's quality of life and absence of resolution after 1 year could be indicators for treating patients …”

Section: Antiviral Therapymentioning

confidence: 99%

ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients

Wollenberg

Oranje²,

Deleuran

et al. 2016

Acad Dermatol Venereol

358

488

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Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as SCORAD. The management of AD must consider the clinical and pathogenic variabilities of the disease and also target flare prevention. Basic therapy includes hydrating topical treatment, as well as avoidance of specific and unspecific provocation factors. Anti-inflammatory treatment of visible skin lesions is based on topical glucocorticosteroids and the topical calcineurin inhibitors tacrolimus and pimecrolimus. Topical calcineurin inhibitors are preferred in sensitive locations. Tacrolimus and mid-potent steroids are proven for proactive therapy, which is long-term intermittent anti-inflammatory therapy of the frequently relapsing skin areas. Systemic anti-inflammatory or immunosuppressive treatment is indicated for severe refractory cases. Biologicals targeting key mechanisms of the atopic immune response are promising emerging treatment options. Microbial colonization and superinfection may induce disease exacerbation and can justify additional antimicrobial treatment. Systemic antihistamines (H1R-blockers) may diminish pruritus, but do not have sufficient effect on lesions. Adjuvant therapy includes UV irradiation, preferably UVA1 or narrow-band UVB 311 nm. Dietary recommendations should be patient specific and elimination diets should only be advised in case of proven food allergy. Allergen-specific immunotherapy to aeroallergens may be useful in selected cases. Psychosomatic counselling is recommended to address stress-induced exacerbations. 'Eczema school' educational programmes have been proven to be helpful for children and adults.

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Section: Antiviral Therapymentioning

confidence: 99%

ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients

Wollenberg

Oranje²,

Deleuran

et al. 2016

Acad Dermatol Venereol

358

488

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“…4 The condition can impact on quality of life, with around 1 in 10 children experiencing a substantial effect on their quality of life. 5 A study in England and Wales described consultation rates during 2006, 6 but there have been no recent studies, nor any studies exploring recent changes over time. 7 Furthermore, no studies have described primary care management, including prescribing and referrals to secondary care.…”

Section: Introductionmentioning

confidence: 99%

Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care

et al. 2015

Self Cite

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“…MC typically presents as one or more umbilicated, smooth, flesh-coloured, domed shaped lesions (3), and is usually diagnosed on clinical examination by a general practitioner or dermatologist (4). The condition can impact on quality of life, with around one in 10 children experiencing a substantial effect on their quality of life (5).…”

Section: Introductionmentioning

confidence: 99%

Affective temperaments and concomitant alcohol use disorders in bipolar disorder

Singh

Forty

Florio

et al. 2015

Journal of Affective Disorders

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Time to resolution and effect on quality of life of molluscum contagiosum in children in the UK: a prospective community cohort study

Cited by 55 publications

References 26 publications

ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients

ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients

Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care

Affective temperaments and concomitant alcohol use disorders in bipolar disorder

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