Time-gated imaging in radiology: theoretical and experimental studies

Grätz, Matthias; Pifferi, Antonio; Wahlström, C.‐G.; Svanberg, Sune

doi:10.1109/2944.577334

Cited by 20 publications

(10 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As first pointed out by Gordon et al 5 and further elaborated theoretically and experimentally by Grätz et al, 6 x-ray time-gated imaging using ultrashort laser-produced x-ray pulses in combination with a time-resolving x-ray detector has the potential to reduce the dose in radiography. This technique relies on the temporal suppression of scattered xray radiation, which can constitute a large part of the signal reaching the image detector.…”

Section: ͓S0003-6951͑98͒02846-0͔mentioning

confidence: 93%

Time-gated x-ray tomography

Grätz

Kiernan

Wahlström

et al. 1998

Applied Physics Letters

Self Cite

View full text Add to dashboard Cite

Time-gated x-ray tomography with scatter reduction is demonstrated using a laser-produced plasma as an ultrashort-pulse x-ray source in combination with a time-resolving streak-camera detector. Backprojections of a phantom imbedded in 9 cm of water show an effective 50% increase in contrast when scattered x-ray quanta (being delayed in time) are suppressed by gating on the prompt, nonscattered photons. Implications for future volumetric tomography, in particular concerning possible dose reductions, are discussed.

show abstract

Section: ͓S0003-6951͑98͒02846-0͔mentioning

confidence: 93%

Time-gated x-ray tomography

Grätz

Kiernan

Wahlström

et al. 1998

Applied Physics Letters

Self Cite

View full text Add to dashboard Cite

show abstract

“…Further, the short temporal duration of the laserproduced x-ray pulses has been utilized in time-gated viewing experiments [37,38] to suppress Compton-scattered photons, potentially allowing a dose reduction in medical x-ray imaging. Normally, such scattered radiation is suppressed employing anti-scattering grids (tunnel vision), but this leads to an increased patient dose, since the grids also block out useful photons.…”

Section: X-ray Generation and Applicationsmentioning

confidence: 99%

Some applications of ultrashort laser pulses in biology and medicine

Svanberg

2001

Meas. Sci. Technol.

View full text Add to dashboard Cite

Ultrashort laser pulses are finding increasing applications in biology and medicine. Such pulses can be used directly or after non-linear modification. Direct utilization includes propagation studies in scattering media with applications in optical mammography, dosimetry for photodynamic therapy and species concentration assessment. Intense continua of electromagnetic radiation of very brief duration are formed in the interaction of focused ultrashort and intense laser pulses with matter. Two different kinds of experiment using such radiation are described, employing visible radiation and x-rays, respectively. Focusing into water leads to the generation of a light continuum through self-phase modulation. The propagation of the light through tissue was studied, addressing questions related to specific tissue chromophore absorption. When terawatt laser pulses are focused onto a solid target with high nuclear charge Z, intense x-ray radiation of few ps duration and with energies exceeding hundreds of keV is emitted. Biomedical applications of this radiation are described, including differential absorption and gated-viewing imaging.

show abstract

“…Further, the short temporal duration of the laser-produced X-ray pulses has been utilized in time-gated viewing experiments~Gordon et Grätz et al, 1996! to suppress Compton-scattered photons, potentially allowing a dose reduction in medical X-ray imaging.…”

Section: X-ray Generation and Applicationsmentioning

confidence: 99%

Generation, characterization, and medical utilization of laser-produced emission continua

et al. 2000

Self Cite

View full text Add to dashboard Cite

Intense continua of electromagnetic radiation of very brief duration are formed in the interaction of focused ultra-short terawatt laser pulses with matter. Two different kinds of experiments, which have been performed utilizing the Lund 10 Hz titanium-doped sapphire terawatt laser system are being described, where visible radiation and X-rays, respectively, have been generated. Focusing into water leads to the generation of a light continuum through self-phase modulation. The propagation of the light through tissue was studied addressing questions related to optical mammography and specific chromophore absorption. When terawatt laser pulses are focused onto a solid target with high nuclear charge Z, intense X-ray radiation of few ps duration and with energies exceeding hundreds of keV is emitted. Biomedical applications of this radiation are described, including differential absorption and gated-viewing imaging.

show abstract

Time-gated imaging in radiology: theoretical and experimental studies

Cited by 20 publications

References 14 publications

Time-gated x-ray tomography

Time-gated x-ray tomography

Some applications of ultrashort laser pulses in biology and medicine

Generation, characterization, and medical utilization of laser-produced emission continua

Contact Info

Product

Resources

About