Time-dose factor (TDF) analysis of dose rate effects in permanent implant dosimetry

Three different intraoperative radiation modalities (electron beam, high-dose-rate brachytherapy, and iodine-125 brachytherapy) in the adjuvant treatment of patients with recurrent colorectal adenocarcinoma

“…Tumors in paraaortic sites had significantly better local control than those in the pelvis (P ϭ 0.03). The 5-year overall survival rate was 4% (median ϭ 20 months; 95% CI, [17][18][19][20][21][22][23]. Patients with microscopic residual disease (P ϭ 0.02) and those treated with postoperative external beam irradiation (EBRT) (P ϭ 0.0007) had statistically significant longer survival.…”

Adjuvant stereotactic permanent seed breast implant: A boost series in view of partial breast irradiation

“…For a permanent seed implant, the total dose D in cGy and TDF are related by Eq. 1, where is the decay constant of the isotope (10,11).…”

Radiation Therapy for Prostate Cancer

“…A modification of the time, dose, and fractionation tables has been made to allow interconvertability between beam radiation and low-dose-rate brachytherapy [36]. There are also substantial practical advantages of brachytherapy, including vastly shorter treatment times and lower costs.…”