Tierexperimentelles über eine Peroral Wirksame Zentralanaleptische Substanz mit Peripherer Kreislaufwirkung

Hauschild, F

doi:10.1007/bf01780551

Cited by 20 publications

(5 citation statements)

References 6 publications

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“…Examination of the literature reveals that these statements can be traced back to early reports (Hauschild 1938;Jacobsen 1939;Tang and Kirch 1971;Cox and Maickel 1972;Peachey et al 1977). However, these experiments either used chronic and complex dosing regimens and/or METH and AMPH were not statistically compared.…”

Section: Discussionmentioning

confidence: 91%

Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats

et al. 2003

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Section: Discussionmentioning

confidence: 91%

Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats

et al. 2003

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“…The compound d-methamphetamine was described as having activity similar to that of amphetamine (Hauschild, 1938), with an enhanced effect on the central nervous system, i.e., wakefulness and euphoria with less intense undesirable side effects. Subjective studies in man (Jacobsen, , 1939, comparing a series of sympathomimetic amines, found dlmethamphetamine somewhat less active than di-amphetamine in "appetite depression" and about equal in other effects.…”

mentioning

confidence: 99%

THE INFLUENCE OF dl‐, d‐, AND l‐AMPHETAMINE AND d‐METHAMPHETAMINE ON A FIXED‐RATIO SCHEDULE

Owen¹

1960

J Exper Analysis Behavior

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In 1910, a systematic pharmacological investigation of a series of aliphatic and aromatic amines (Barger & Dale, 1910) revealed a number of compounds that had properties similar to those of epinephrine. These compounds elicited physiological responses of varying degree similar to functional stimulation of the sympathetic nervous system. From this work the term sympathomimetic amine was coined. Prior to this (in the 1880's), ephedrine, the active principle of the Chinese herb Ma Huang, had been studied and was discarded as being too toxic. Upon reinvestigation by Chen and Schmidt (1924), the pharmacological importance of ephedrine as a sympathomimetic was recognized. Publication of this work stimulated new interest in these amine compounds, especially the phenylethylamines and the phenylisopropylamines, the chemical nucleus structures of epinephrine and ephedrine, respectively.

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“…Intestinal Effects.-Hauschild (15) reported that d-desoxyephedrine counteracted pilocarpine or arecoline spasms of the isolated rabbit intestine a t a concentration of 1 : 100,000.…”

Section: Graham Et A/ (Lo) Using the United Statesmentioning

confidence: 99%

“…Blood Pressure.-Hauschild (15) reported that 10 micrograms of d-des0xyephedrin.e intravenously in cats and do& caused a blood pressure rise almost as great as that produced by ephedrine. Doses of 50-100 micrograms caused a prolonged rise.…”

Section: Experimental Pharmacologymentioning

confidence: 99%

Desoxyephedrine—a review of the literature

Haley¹

1947

Journal of the American Pharmaceutical Association (Scientific

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Tierexperimentelles über eine Peroral Wirksame Zentralanaleptische Substanz mit Peripherer Kreislaufwirkung

Cited by 20 publications

References 6 publications

Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats

Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats

THE INFLUENCE OF dl‐, d‐, AND l‐AMPHETAMINE AND d‐METHAMPHETAMINE ON A FIXED‐RATIO SCHEDULE

Desoxyephedrine—a review of the literature

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