Ticlopidine-Induced Lupus

Spiera, Robert; Berman, Rosanne S.; Werner, Andrew; Spiera, Harry

doi:10.1001/archinte.162.19.2240

Cited by 22 publications

(3 citation statements)

References 12 publications

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“…Ticlopidine has been recently described in 2002 in a series of four cases. 46 Antihypertensives. Beta-blockers, most recently acebutolol have been implicated in causing SCLE.…”

Section: Commonly Used Drugsmentioning

confidence: 99%

Drug-induced lupus: an update

Vasoo

2006

Lupus

140

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Drug-induced lupus erythematosus (DILE) is a lupus-like illness that has been recognized as an entity under environmentally-induced lupus erythematosus, where other agents such as physical (ultra-violet irradiation), chemical (heavy metals, aromatic amines) and food products (alfalfa sprouts) have been implicated. DILE has been accepted as a side effect of therapy with over 80 drugs since its first description in association with sulfadiazine in 1945. The epidemiology and clinical course of SLE and DILE differ markedly and prognosis is generally favourable in the latter although occasional life-threatening cases have been reported in the literature. Constant pharmacovigilance is crucial for prompt diagnosis and cessation of offending therapy offers the best outcome. This review discusses the clinical presentation, diagnosis of DILE as well as provides an update on postulated pathogenic mechanisms and an overview of implicated drugs.

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“…Ticlopidine has been recently described in 2002 in a series of four cases. 46 Antihypertensives. Beta-blockers, most recently acebutolol have been implicated in causing SCLE.…”

Section: Commonly Used Drugsmentioning

confidence: 99%

Drug-induced lupus: an update

Vasoo

2006

Lupus

140

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“…Недавно было обнаружено 8-кратное повышение относительного риска возникновения ЛВ вследствие приема тетрациклинов [16]. В 2002 г. появилось сообщение о 4 случаях развития ЛВ на фоне тиклопидина [17]. Предполагается, что число потенциальных «виновников» ЛВ будет только расти.…”

Section: историческая справкаunclassified

Drug-induced lupus

Клюквина¹,

Гунчикова

Aa³

2018

Sovremennaâ revmatologiâ

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Drug-induced lupus (DIL) is an autoimmune phenomenon that has similar clinical and laboratory manifestations with idiopathic systemic lupus erythematosus (SLE). About 100 drugs are now known to be associated with the development of DIL. Its diagnosis is verified in the presence of a chronological relationship between the long-term administration of drugs and the mandatory presence of one clinical and one laboratory diagnostic criteria for SLE.The paper deals with the etiology, pathogenesis, and differential diagnosis of DIL. It presents a spectrum of drugs that can cause DIL and considers the features of its different forms.Based on the recent data available in the literature, the authors analyze the occurrence of autoimmune responses due to the useof biologic agents (BAs), primarily tumor necrosis factor-αinhibitors. Therapeutic approaches for DIL are discussed. Recommendations are given for screening the patients in the use of BAs. Clinical examples are provided.

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“…La ticlopidina è un antiaggregante capace di indurre patologie immunomediate come per esempio: porpora trombocitica trombocitopenica e DILE. In letteratura sono stati descritti infatti, quattro casi di lupus-like syndrome (64). L'amiodarone è un antiaritmico di terza generazione capace di indurre una lupus-like syndrome associata a endocardite verrucosa e versamento pleuro-pericardico (65).…”

Section: Terza Categoriaunclassified

Drug-induced lupus erythematosus

Atzeni¹,

Marrazza²,

Sarzi‐Puttini³

et al. 2011

Reumatismo

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Drug-induced lupus is a syndrome which share symptoms and laboratory characteristics with the idiopathic systemic lupus erythematosus (SLE). The list of medications implicated as etiologic agents in drug-induced lupus continues to grow. The terms used for this condition are lupus-like syndrome, drug-induced lupus erythematosus (DILE) and drug related lupus. More than 80 drugs have been associated with DILE. The first case of DILE was reported in 1945 and associated with sulfadiazin. In 1953 it was reported that DILE was related to the use of hydralazine. Drugs responsible for the development of DILE can divided into three groups, but the list of these drugs is quite long because new drugs are included yearly in the list. The syndrome is characterised by arthralgia, myalgia, pleurisy, rash and fever in association with antinuclear antibodies in the serum. Recognition of DILE is important because it usually reverts within a few weeks after stopping the drug

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Ticlopidine-Induced Lupus

Cited by 22 publications

References 12 publications

Drug-induced lupus: an update

Drug-induced lupus: an update

Drug-induced lupus

Drug-induced lupus erythematosus

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